Browsing byAuthorHyeon, Seung Jae

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Showing results 11 to 37 of 37

Issue DateTitleAuthor(s)
2022-09Decreased FAK activity and focal adhesion dynamics impair proper neurite formation of medium spiny neurons in Huntington's diseaseLee, Hae Nim; Hyeon, Seung Jae; Kim, Heejung; Sim, Kyoung Mi; Kim, Yunha; Ju, Jeongmin; Lee, Junghee; Wang, Yingxiao; Ryu, Hoon; Seong, Jihye
2020-05Distinct dual roles of p-Tyr42 RhoA GTPase in tau phosphorylation and ATP citrate lyase activation upon different A beta concentrationsCap, Kim Cuong; Jung, Yeon-Joo; Choi, Bo Young; Hyeon, Seung Jae; Kim, Jae-Gyu; Min, Jung-Ki; Islam, Rokibul; Hossain, Abu Jubayer; Chung, Won-Suk; Suh, Sang Won; Ryu, Hoon; Park, Jae-Bong
2021-09Dysfunction of X-linked inhibitor of apoptosis protein (XIAP) triggers neuropathological processes via altered p53 activity in Huntington's diseaseHyeon, Seung Jae; Park, Jinyoung; Yoo, Junsang; Kim, Su-Hyun; Hwang, Yu Jin; Kim, Seung-Chan; Liu, Tian; Shim, Hyun Soo; Kim, Yunha; Cho, Yakdol; Woo, Jiwan; Kim, Key-Sun; Myers, Richard H.; Ryu, Hannah L.; Kowall, Neil W.; Song, Eun Joo; Hwang, Eun Mi; Seo, Hyemyung; Lee, Junghee; Ryu, Hoon
2019-09-23Elevation of endoplasmic reticulum (ER) stress-mediated Ca2+ release leads to tauopathy in chronic traumatic encephalopathy (CTE)Im, Hyeon joo; Kim, Yun ha; Lim, Sung su; Kim, Yun Kyung; Hyeon, Seung Jae; Junghee Lee; Neil W. Kowall; Chung, Soo young; Ann C. McKee; Hoon Ryu
2020-06Epigenome signatures landscaped by histone H3K9me3 are associated with the synaptic dysfunction in Alzheimer's diseaseLee, Min Young; Lee, Junghee; Hyeon, Seung Jae; Cho, Hyesun; Hwang, Yu Jin; Shin, Jong-Yeon; McKee, Ann C.; Kowall, Neil W.; Kim, Jong-Il; Stein, Thor D.; Hwang, Daehee; Ryu, Hoon
2019-07-01EWSR1, a multifunctional protein, regulates cellular function and aging via genetic and epigenetic pathwaysLee, Junghee; Nguyen, Phuong T.; Shim, Hyun Soo; Hyeon, Seung Jae; Im, Hyeonjoo; Choi, Mi-Hyun; Chung, Sooyoung; Kowall, Neil W.; Lee, Sean Bong; Ryu, Hoon
2018-04Genetic Ablation of EWS RNA Binding Protein 1 (EWSR1) Leads to Neuroanatomical Changes and Motor Dysfunction in MiceYoon, Yeojun; Park, Hasang; Kim, Sangyeon; Nguyen, Phuong T.; Hyeon, Seung Jae; Chung, Sooyoung; Im, Hyeonjoo; Lee, Junghee; Lee, Sean Bong; Ryu, Hoon
2021-09Hevin-calcyon interaction promotes synaptic reorganization after brain injuryKim, Jong-Heon; Jung, Hyun-Gug; Kim, Ajung; Shim, Hyun Soo; Hyeon, Seung Jae; Lee, Young-Sun; Han, Jin; Jung, Jong Hoon; Lee, Jaekwang; Ryu, Hoon; Park, Jae-Yong; Hwang, Eun Mi; Suk, Kyoungho
2017-02-28Increased acetylation of Peroxiredoxin1 by HDAC6 inhibition leads to recovery of A beta-induced impaired axonal transportChoi, Heesun; Kim, Haeng Jun; Kim, Jisoo; Kim, Soohyun; Yang, Jinhee; Lee, Wonik; Park, Yeonju; Hyeon, Seung Jae; Lee, Dong-Sup; Ryu, Hoon; Chung, Junho; Mook-Jung, Inhee
2021-02L-Citrulline Level and Transporter Activity Are Altered in Experimental Models of Amyotrophic Lateral SclerosisGyawali, Asmita; Gautam, Shashi; Hyeon, Seung Jae; Ryu, Hoon; Kang, Young-Sook
2023-04Lipocalin-2 Is a Key Regulator of Neuroinflammation in Secondary Traumatic and Ischemic Brain InjuryKim, Jae-Hong; Kang, Ri Jin; Hyeon, Seung Jae; Ryu, Hoon; Joo, Hyejin; Bu, Youngmin; Kim, Jong-Heon; Suk, Kyoungho
2022-12Modulation of histone H3K4 dimethylation by spermidine ameliorates motor neuron survival and neuropathology in a mouse model of ALSChoi, Seung-Hye; Yousefian-Jazi, Ali; Hyeon, Seung Jae; Nguyen, Phuong Thi Thanh; Chu, Jiyeon; Kim, Sojung; Kim, Suhyun; Ryu, Hannah L.; Kowall, Neil W.; Ryu, Hoon; Lee, Junghee
2021-01Modulation of SETDB1 activity by APQ ameliorates heterochromatin condensation, motor function, and neuropathology in a Huntington's disease mouse modelHwang, Yu Jin; Hyeon, Seung Jae; Kim, Younghee; Lim, Sungsu; Lee, Min Young; Kim, Jieun; ASHWINI, MACHHINDRA LONDHE; Gotina, Lizaveta; Kim, Yunha; Pae, Ae Nim; Cho, Yong Seo; Seong, Jihye; Seo, Hyemyung; Kim, Yun Kyung; Choo, Hyunah; Ryu, Hoon; Min, Sun-Joon
2022-01Monocarboxylate transporter functions and neuroprotective effects of valproic acid in experimental models of amyotrophic lateral sclerosisGyawali, Asmita; Latif, Sana; Choi, Seung-Hye; Hyeon, Seung Jae; Ryu, Hoon; Kang, Young-Sook
2024-03Neurotoxic Microglial Activation via IFNγ-Induced Nrf2 Reduction Exacerbating Alzheimer's DiseaseKang, You Jung; Hyeon, Seung Jae; Mcquade, Amanda; Lim, Jiwoon; Baek, Seung Hyun; Diep, Yen N.; Do, Khanh V.; Jeon, Yeji; Jo, Dong-Gyu; Lee, C. Justin; Blurton-Jones, Mathew; Ryu, Hoon; Cho, Hansang
2021-02Power Failure of Mitochondria and Oxidative Stress in Neurodegeneration and Its Computational ModelsWoo, JunHyuk; Cho, Hyesun; Seol, YunHee; Kim, Soon Ho; Park, Chanhyeok; Yousefian-Jazi, Ali; Hyeon, Seung Jae; Lee, Junghee; Ryu, Hoon
2020-06-17PyrPeg, a Blood-Brain-Barrier-Penetrating Two-Photon Imaging Probe, Selectively Detects Neuritic Plaques, Not Tau AggregatesChoi, Ji-Woo; Ju, Yeon Ha; Choi, Yunsook; Hyeon, Seung Jae; Gadhe, Changdev G.; Park, Jong-Hyun; Kim, Mun Seok; Baek, Seungyeop; Kim, YoungSoo; Park, Ki Duk; Pae, Ae Nim; Ryu, Hoon; Lee, C. Justin; Cho, Bong Rae
2019-06Quantitative Proteomic Analysis Reveals Impaired Axonal Guidance Signaling in Human Postmortem Brain Tissues of Chronic Traumatic EncephalopathyBi, Baibin; Choi, Han-Pil; Hyeon, Seung Jae; Sun, Shengnan; Su, Ning; Liu, Yuguang; Lee, Junghee; Kowall, Neil W.; McKee, Ann C.; Yang, Jing-Hua; Ryu, Hoon
2017-11Remodeling of heterochromatin structure slows neuropathological progression and prolongs survival in an animal model of Huntington's diseaseLee, Junghee; Hwang, Yu Jin; Kim, Yunha; Lee, Min Young; Hyeon, Seung Jae; Lee, Soojin; Kim, Dong Hyun; Jang, Sung Jae; Im, Hyoenjoo; Min, Sun-Joon; Choo, Hyunah; Pae, Ae Nim; Kim, Dong Jin; Cho, Kyung Sang; Kowall, Neil W.; Ryu, Hoon
2018-02SIRT3 deregulation is linked to mitochondrial dysfunction in Alzheimer's diseaseLee, Junghee; Kim, Yunha; Liu, Tian; Hwang, Yu Jin; Hyeon, Seung Jae; Im, Hyeonjoo; Lee, Kyungeun; Alvarez, Victor E.; McKee, Ann C.; Um, Soo-Jong; Hur, Manwook; Mook-Jung, Inhee; Kowall, Neil W.; Ryu, Hoon
2021-04The Alteration of L-Carnitine Transport and Pretreatment Effect under Glutamate Cytotoxicity on Motor Neuron-Like NSC-34 LinesGyawali, Asmita; Hyeon, Seung Jae; Ryu, Hoon; Kang, Young-Sook
2017-05Transcriptome analyses of chronic traumatic encephalopathy show alterations in protein phosphatase expression associated with tauopathySeo, Jeong-Sun; Lee, Seungbok; Shin, Jong-Yeon; Hwang, Yu Jin; Cho, Hyesun; Yoo, Seong-Keun; Kim, Yunha; Lim, Sung su; Kim, Yun Kyung; Hwang, Eun Mi; Kim, Su Hyun; Kim, Chong-Hyun; Hyeon, Seung Jae; Yun, Ji-Young; Kim, Jihye; Kim, Yona; Alvarez, Victor E.; Stein, Thor D.; Lee, Junghee; Kim, Dong Jin; Kim, Jong-Il; Kowall, Neil W.; Ryu, Hoon; McKee, Ann C.
2021-06"Turn-On" Quinoline-Based Fluorescent Probe for Selective Imaging of Tau Aggregates in Alzheimer's Disease: Rational Design, Synthesis, and Molecular DockingElbatrawy, Ahmed A.; Hyeon, Seung Jae; Yue, Nan; Osman, Essam Eldin A.; Choi, Seung Hyeo; Lim, Sungsu; Kim, Yun Kyung; Ryu, Hoon; Cui, Mengchao; Nam, Ghilsoo
2021-06UBE4B, a microRNA-9 target gene, promotes autophagy-mediated Tau degradationSubramanian, Manivannan; Hyeon, Seung Jae; Das, Tanuza; Suh, Yoon Seok; Kim, Yun Kyung; Lee, Jeong-Soo; Song, Eun Joo; Ryu, Hoon; Yu, Kweon
2020-04Visualization of soluble tau oligomers in TauP301L-BiFC transgenic mice demonstrates the progression of tauopathyShin, Seulgi; Kim, Dohee; Song, Ji Yeon; Jeong, Hyeanjeong; Hyeon, Seung Jae; Kowall, Neil W.; Ryu, Hoon; Pae, Ae Nim; Lim, Sungsu; Kim, Yun Kyung
2022-05-20Visualization of soluble tau oligomers in the brain of TauP301L-BiFC transgenic mice reveals consequential events of tau aggregationSeulgi Shin; Kim, Dohee; Song Ji Yeon; Jeong, Hyeanjeong; Hyeon, Seung Jae; Kowall, Neil W.; Ryu, Hoon; Pae, Ae Nim; Lim, Sung su; Kim, Yun Kyung
2023-07Visualizing reactive astrocyte-neuron interaction in Alzheimer’s disease using 11C-acetate and 18F-FDGNam, Min-Ho; Ko, Hae Young; Kim, Dongwoo; Lee, Sangwon; Park, Yongmin Mason; Hyeon, Seung Jae; Won, Woojin; Chung, Jee-In; Kim, Seon Yoo; Jo, Han Hee; Oh, Kyeong Taek; Han, Young-Eun; Lee, Gwan-Ho; Ju, Yeon Ha; Lee, Hyowon; Kim, Hyunjin; Heo, Jaejun; Bhalla, Mridula; Kim, Ki Jung; Kwon, Jea; Stein, Thor D.; Kong, Mingyu; Lee, Hyunbeom; Lee, Seung Eun; Oh, Soo-Jin; Chun, Joong-Hyun; Park, Mi-Ae; Park, Ki Duk; Ryu, Hoon; Yun, Mijin; Lee, C. Justin

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