Browsing byAuthorPark, Ki Duk
Showing results 22 to 51 of 89
| Issue Date | Title | Author(s) |
|---|---|---|
| 2017-06-15 | Design, synthesis, biological evaluation and molecular modelling of 2-(2-aryloxyphenyl)-1,4-dihydroisoquinolin-3(2H)-ones: A novel class of TSPO ligands modulating amyloid-beta-induced mPTP opening | Elkamhawy, Ahmed; Park, Jung-eun; Hassan, Ahmed H. E.; Pae, Ae Nim; Lee, Jiyoun; Park, Beoung-Geon; Paik, Sora; Do, Jimin; Park, Jong-Hyun; Park, Ki Duk; Moon, Bongjin; Park, Woo Kyu; Cho, Heeyeong; Jeong, Dae Young; Roh, Eun Joo |
| 2021-02-15 | Development and optimization of halogenated vinyl sulfones as Nrf2 activators for the treatment of Parkinson's disease | Choi, Ji Won; Kim, Siwon; Yoo, Jong Seok; Kim, Hyeon Jeong; Kim, Hyeon Ji; Kim, Byung Eun; Lee, Elijah Hwejin; Lee, Yong Sup; Park, Jong-Hyun; Park, Ki Duk |
| 2022-04 | Development of Dibenzothiazepine Derivatives as Multifunctional Compounds for Neuropathic Pain | Jung, Young-Hwan; Kim, Yeo Ok; Kang, Koon Mook; Lee, Hyung Gon; Son, Borum; Han, Xuehao; Oh, Eunseok; Kim, Siwon; Seo, Seon Hee; Park, Jong-Hyun; Park, Ki Duk; Kim, Woong Mo; Yoon, Myung Ha; Kim, Yong-Chul |
| 2014-05-28 | Differential regulation of collapsin response mediator protein 2 (CRMP2) phosphorylation by GSK3 beta and CDK5 following traumatic brain injury | Wilson, Sarah M.; Yeon, Seul Ki; Yang, Xiao-Fang; Park, Ki Duk; Khanna, Rajesh |
| 2015-12-15 | Discovery of 2-aryloxy-4-amino-quinazoline derivatives as novel protease-activated receptor 2 (PAR(2)) antagonists | Cho, Nam-Chul; Cha, Ji Hyoun; Kim, Hyojin; Kwak, Jinsook; Kim, Dohee; Seo, Seung-Hwan; Shin, Ji-Sun; Kim, TaeHun; Park, Ki Duk; Lee, Jiyoun; No, Kyoung Tai; Kim, Yun Kyung; Lee, Kyung-Tae; Pae, Ae Nim |
| 2021-11 | Discovery of 3,4-dichloro-N-(1H-indol-5-yl)benzamide: A highly potent, selective, and competitive hMAO-B inhibitor with high BBB permeability and action | Elkamhawy, Ahmed; Kim, Hyeon Jeong; Elsherbeny, Mohamed H.; Paik, Sora; Park, Jong-Hyun; Gotina, Lizaveta; Abdellattif, Magda H.; Gouda, Noha A.; Cho, Jungsook; Lee, Kyeong; Pae, Ae Nim; Park, Ki Duk; Roh, Eun Joo |
| 2017-01-05 | Discovery of benzimidazole derivatives as modulators of mitochondrial function: A potential treatment for Alzheimer's disease | Kim, TaeHun; Yang, Ha Yun; Park, Beoung Gun; Jung, Seo Yun; Park, Jong-Hyun; Park, Ki Duk; Min, Sun-Joon; Tae, Jinsung; Yang, Hyejin; Cho, Suengmok; Cho, Sung Jin; Song, Hyundong; Mook-Jung, Inhee; Lee, Jiyoun; Pae, Ae Nim |
| 2013-03 | Discovery of Lacosamide Affinity Bait Agents That Exhibit Potent Voltage-Gated Sodium Channel Blocking Properties | Park, Ki Duk; Yang, Xiao-Fang; Lee, Hyosung; Dustrude, Erik T.; Wang, Yuying; Khanna, Rajesh; Kohn, Harold |
| 2020-01 | Discovery of N-(1-(3-fluorobenzoyl)-1H-indol-5-yl)pyrazine-2-carboxamide: a novel, selective, and competitive indole-based lead inhibitor for human monoamine oxidase B | Elkamhawy, Ahmed; Paik, Sora; Kim, Hyeon Jeong; Park, Jong-Hyun; Londhe, Ashwini M.; Lee, Kyeong; Pae, Ae Nim; Park, Ki Duk; Roh, Eun Joo |
| 2019-10-17 | Discovery of Novel Biased Opioid Receptor Ligands through Structure-Based Pharmacophore Virtual Screening and Experiment | Jeong, Pyeonghwa; Kim, Soo-Kyung; Li, Quanjie; Oh, Su-jin; Son, Seonil; Chen, Guangju; Tan, Hongwei; Kim, Siwon; Park, Jong-Hyun; Park, Ki Duk; Kim, Yeo Ok; Yoon, Myung Ha; Kim, Yong-Chul; Goddard, William A., III |
| 2022-02 | Discovery of Novel Sphingosine-1-Phosphate-1 Receptor Agonists for the Treatment of Multiple Sclerosis | Park, Sun Jun; Yeon, Seul Ki; Yoowon Kim; Kim, Hyeon Jeong; KIm Si Won; KIM, JU SHIN; Choi, Ji Won; Byung, Eun Kim; Elijah, Hwejin Lee; Kim Ri-um; SEO, SEON HEE; Lee, Jae Ick; Jun Woo Kim; Ha-Yeon Lee; Hayoung Hwang; Yong-Sun Bahn; Eunji Cheong; Park, Jong Hyun; Park, Ki Duk |
| 2017-12-01 | Discovery of thienopyrrolotriazine derivatives to protect mitochondrial function against A beta-induced neurotoxicity | Kim, TaeHun; Son, Woo Seung; Morshed, Mohammad Neaz; Londhe, Ashwini M.; Jung, Seo Yun; Park, Jong-Hyun; Park, Woo-Kyu; Lim, Sang Min; Park, Ki Duk; Cho, Sung Jin; Jeong, Kyu-Sung; Lee, Jiyoun; Pae, Ae Nim |
| 2014-02-27 | Discovery of Vinyl Sulfones as a Novel Class of Neuroprotective Agents toward Parkinson's Disease Therapy | Woo, Seo Yeon; Kim, Ji Hyun; Moon, Mi Kyeong; Han, Se-Hee; Yeon, Seul Ki; Choi, Ji Won; Jang, Bo Ko; Song, Hyo Jung; Kang, Yong Gu; Kim, Jin Woo; Lee, Jaeick; Kim, Dong Jin; Hwang, Onyou; Park, Ki Duk |
| 2021-03 | Editorial: Interactions Between Small Molecule Ligands and Target Enzymes | Kim, Sung-Kun; Park, Ki Duk; Lee, Dong-Woo |
| 2020-07-07 | Excessive Astrocytic GABA Causes Cortical Hypometabolism and Impedes Functional Recovery after Subcortical Stroke | Nam, Min-Ho; Cho, Jongwook; Kwon, Dae-Hyuk; Park, Ji-Young; Woo, Junsung; Lee, Jungmoo; Lee, Sangwon; Ko, Hae Young; Won, Woojin; Kim, Ra Gyung; Song, Hanlim; Oh, Soo-Jin; Choi, Ji Won; Park, Ki Duk; Park, Eun Kyung; Jung, Haejin; Kim, Hyung-Seok; Lee, Min-Cheol; Yun, Mijin; Lee, C. Justin; Kim, Hyoung-Ihl |
| 2023-08 | Exploration of Tetrahydroisoquinoline- and Benzo[c]azepine-Based Sphingosine 1-Phosphate Receptor 1 Agonists for the Treatment of Multiple Sclerosis | Cha, Eunji; Kim, Jushin; Gotina, Lizaveta; Kim, Jaehwan; Kim, Hyeon Jeong; Seo, Seon Hee; Park, Jeong-Eun; Joo, Jeongmin; Kang, Minsik; Lee, Jaeick; Hwang, Hayoung; Kim, Hak Joong; Pae, Ae Nim; Park, Ki Duk; Park, Jong-Hyun; Lim, Sang Min |
| 2019-01-15 | First-in-class DAPK1/CSF1R dual inhibitors: Discovery of 3,5-dimethoxy-N-(4-(4-methoxyphenoxy)-24(6-morpholinopyridin-3-yl)amino) pyrimidin-5-yl)benzamide as a potential anti-tauopathies agent | Farag, Ahmed Karam; Hassan, Ahmed H. E.; Jeong, Hyeanjeong; Kwon, Youngji; Choi, Jin Gyu; Oh, Myung Sook; Park, Ki Duk; Kim, Yun Kyung; Roh, Eun Joo |
| 2020-06 | Fluorinated CRA13 analogues: Synthesis, in vitro evaluation, radiosynthesis, in silico and in vivo PET study | Hassan, Ahmed H. E.; Park, Kyung Tae; Kim, Hye Jin; Lee, Hyo Jong; Kwon, Yeong Ho; Hwang, Ji Young; Jang, Choon-Gon; Chung, Jin Hwa; Park, Ki Duk; Lee, Sang Joo; Oh, Seung Jun; Lee, Yong Sup |
| 2020-11 | Four-week repeated dose oral toxicity study of KDS2010, a novel selective monoamine oxidase B inhibitor, in Sprague Dawley rats | Kim, Kyung-Tai; Kim, Da-Hee; Kim, Bo-Kyung; Han, Ji-Seok; Eom, Han Young; Yang, Mi-Jin; Shin, Seung-Hyuk; Cho, Doo-Wan; Jang, Bo Ko; Park, Ki Duk; Yang, Young-Su; Han, Su-Cheol |
| 2016-09-16 | Glycyrrhizic acid prevents astrocyte death by neuromyelitis optica-specific IgG via inhibition of C1q binding | Kim, Ji-Sun; Cheon, Soyoung; Kim, Seung Woo; Kim, Boram; Kim, Heejaung; Park, Ki Duk; Kim, Sung-Min |
| 2016-12 | Hydroxycholesterol Levels in the Serum and Cerebrospinal Fluid of Patients with Neuromyelitis Optica Revealed by LC-Ag+CIS/MS/MS and LC-ESI/MS/MS with Picolinic Derivatization: Increased Levels and Association with Disability during Acute Attack | Cha, Eunju; Lee, Kang Mi; Park, Ki Duk; Park, Kyung Seok; Lee, Kwang-Woo; Kim, Sung-Min; Lee, Jaeick |
| 2023-09 | Hypothalamic GABRA5-positive neurons control obesity via astrocytic GABA | Sa, Moonsun; Yoo, Eun-Seon; Koh, Wuhyun; Park, Mingu Gordon; Jang, Hyun-Jun; Yang, Yong Ryoul; Bhalla, Mridula; Lee, Jae-Hun; Lim, Jiwoon; Won, Woojin; Kwon, Jea; Kwon, Joon-Ho; Seong, Yejin; Kim, Byungeun; An, Heeyoung; Lee, Seung Eun; Park, Ki Duk; Suh, Pann-Ghill; Sohn, Jong-Woo; Lee, C. Justin |
| 2020-12 | Identification and evaluation of a napyradiomycin as a potent Nrf2 activator: Anti-oxidative and anti-inflammatory activities | Choi, Ji Won; Kim, Geum Jin; Kim, Hyeon Jeong; Nam, Joo-Won; Kim, Jushin; Chin, Jungwook; Park, Jong-Hyun; Choi, Hyukjae; Park, Ki Duk |
| 2016-12 | Identification of the first in silico-designed TREK1 antagonists that block channel currents dose dependently | Viswanath, Ambily Nath Indu; Jung, Seo Yun; Hwang, Eun Mi; Park, Ki Duk; Lim, Sang Min; Min, Sun-Joon; Cho, Yong Seo; Pae, Ae Nim |
| 2017-07 | Indole-Substituted Benzothiazoles and Benzoxazoles as Selective and Reversible MAO-B Inhibitors for Treatment of Parkinson's Disease | Nam, Min-Ho; Park, Moosung; Park, Hyeri; Kim, Youngjae; Yoon, Seulki; Sawant, Vikram Shahaji; Choi, Ji Won; Park, Jong-Hyun; Park, Ki Duk; Min, Sun-Joon; Lee, C. Justin; Chooaii, Hyunah |
| 2022-08 | Inhibiting peripheral and central MAO-B ameliorates joint inflammation and cognitive impairment in rheumatoid arthritis | Won, Woojin; Choi, Hyun-Ji; Yoo, Ji-Young; Kim, Daeun; Kim, Tai Young; Ju, YeonHa; Park, Ki Duk; Lee, Hyunbeom; Jung, Sang Youn; Lee, C. Justin |
| 2022-02 | Inhibition of monoamine oxidase B prevents reactive astrogliosis and scar formation in stab wound injury model | Chun, Heejung; Lim, Jiwoon; Park, Ki Duk; Lee, C. Justin |
| 2021-07 | KDS2010, a Newly Developed Reversible MAO-B Inhibitor, as an Effective Therapeutic Candidate for Parkinson's Disease | Nam, Min-Ho; Park, Jong-Hyun; Song, Hyo jung; Choi, Ji Won; Kim, Siwon; 장보고; Yoon, Hyung Ho; Heo, Jun Young; Lee, Hyowon; An, Heeyoung; Kim, Hyeon Jeong; Park, Sun Jun; Cho, Doo-Wan; Yang, Young-Su; Han, Su-Cheol; Kim, Sangwook; Oh, Soo-Jin; Jeon, Sang Ryong; Park, Ki Duk; Lee, C. Justin |
| 2024-04 | KDS2010, a reversible MAO-B inhibitor, extends the lifetime of neural probes by preventing glial scar formation | Chae, Uikyu; Chun, Heejung; Lim, Jiwoon; Shin, Hyogeun; Smith, Wesley Charles; Choi, Ji Won; Park, Ki Duk; Lee, C. Justin; Cho, Il-Joo |
| 2022-05 | Longitudinal intravital imaging of cerebral microinfarction reveals a dynamic astrocyte reaction leading to glial scar formation | Lee, Jingu; Kim, Joon-Goon; Hong, Sujung; Kim, Young Seo; Ahn, Soyeon; Kim, Ryul; Chun, Heejung; Park, Ki Duk; Jeong, Yong; Kim, Dong-Eog; Lee, C. Justin; Ku, Taeyun; Kim, Pilhan |
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