Showing results 57 to 86 of 89
Issue Date | Title | Author(s) |
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2019-06 | Leveraging Compound Promiscuity to Identify Targetable Cysteines within the Kinome | Rao, Suman; Gurbani, Deepak; Du, Guangyan; Everley, Robert A.; Browne, Christopher M.; Chaikuad, Apirat; Tan, Li; Schroeder, Martin; Gondi, Sudershan; Ficarro, Scott B.; Sim, Taebo; Kim, Nam Doo; Berberich, Matthew J.; Knapp, Stefan; Marto, Jarrod A.; Westover, Kenneth D.; Sorger, Peter K.; Gray, Nathanael S. |
2013-12 | New diarylamides and diarylureas possessing 8-amino(acetamido) quinoline scaffold: Synthesis, antiproliferative activities against melanoma cell lines, kinase inhibition, and in silico studies | Koh, Eun Jeong; El-Gamal, Mohammed I.; Oh, Chang-Hyun; Lee, So Ha; Sim, Taebo; Kim, Garam; Choi, Hong Seok; Hong, Jun Hee; Lee, Sang-gi; Yoo, Kyung Ho |
2012-05-01 | New diarylureas and diarylamides possessing acet(benz)amidophenyl scaffold: Design, synthesis, and antiproliferative activity against melanoma cell line | Kim, Hee Jin; Cho, Hye Jung; Kim, Hwan; El-Gamal, Mohammed I.; Oh, Chang-Hyun; Lee, So Ha; Sim, Taebo; Hah, Jung-Mi; Yoo, Kyung Ho |
2015-06 | Non-receptor tyrosine kinase inhibitors enhances beta-cell survival by suppressing the PKC delta signal transduction pathway in streptozotocin - induced beta-cell apoptosis | Karunakaran, Udayakumar; Park, Si Jun; Jun, Do Youn; Sim, Taebo; Park, Keun-Gyu; Kim, Myoung Ok; Lee, In Kyu |
2013-07 | Novel Quinolinylaminoisoquinoline Bioisosteres of Sorafenib as Selective RAFI Kinase Inhibitors: Design, Synthesis, and Antiproliferative Activity against Melanoma Cell Line | Cho, Hye Jung; El-Gamal, Mohammed Ibrahim; Oh, Chang-Hyun; Lee, So Ha; Sim, Taebo; Kim, Garam; Choi, Hong Seok; Choi, Jung Hoon; Yoo, Kyung Ho |
2012-03 | Novel small molecule Raf kinase inhibitors for targeted cancer therapeutics | Kim, Do-Hee; Sim, Taebo |
2015-03 | One step synthesis of quantum dot-magnetic nanoparticle heterodimers for dual modal imaging applications | Lee, Jiyeon; Hwang, Gyoyeon; Hong, Yeon Sun; Sim, Taebo |
2015-01 | Optimization of Bipyridinyl Pyrazole Scaffolds via Design, Synthesis and Screening of a New Series of ROS1 Kinase-modulating Compounds | Al-Sanea, Mohammad M.; Park, Byung Sun; Abdelazem, Ahmed Z.; Selim, Khalid B.; Yoo, Kyung Ho; Sim, Taebo; Tae, Jin Sung; Lee, So Ha |
2014-12 | Pharmacological targeting of the pseudokinase Her3 | Xie, Ting; Lim, Sang Min; Westover, Kenneth D.; Dodge, Michael E.; Ercan, Dalia; Ficarro, Scott B.; Udayakumar, Durga; Gurbani, Deepak; Tae, Hyun Seop; Riddle, Steven M.; Sim, Taebo; Marto, Jarrod A.; Jaenne, Pasi A.; Crews, Craig M.; Gray, Nathanael S. |
2009-03 | Pharmacophore based 3D-QSAR study of VEGFR-2 inhibitors | Neaz, M. M.; Pasha, F. A.; Muddassar, M.; Lee, So Ha; Sim, Taebo; Hah, Jung-Mi; Cho, Seung Joo |
2019-01 | Procaspase activating compound 1 controls tetracycline repressor-regulated gene expression system | Song, Chiman; Kim, Namkyoung; Park, Miri; Lee, Jiyeon; Oh, Ki-Bong; Sim, Taebo |
2019-05 | Raman-Based in Situ Monitoring of Changes in Molecular Signatures during Mitochondrially Mediated Apoptosis | Shin, Hyeon Jeong; Lee, Ji Hye; Kim, Yong Duk; Shin, Injae; Sim, Taebo; Lim, Dong-Kwon |
2012-02-18 | Rhodium-catalyzed reductive cyclization of 1,6-enynes and stereoselective synthesis of the putative structure of lucentamycin A and its stereoisomers | Ham, Young Jin; Yu, Hana; Kim, Nam Doo; Hah, Jung-Mi; Selim, Khalid B.; Choi, Hwan Geun; Sim, Taebo |
2013-12-02 | Stereoselective Synthesis of (+)-Polyoxamic Acid Starting with a Chiral Aziridine | Yoon, Hojong; Sim, Taebo |
2013-02-06 | Stereoselective synthesis of (-)-8-epi-swainsonine starting with a chiral aziridine | Lee, Baeck Kyoung; Choi, Hwan Geun; Roh, Eun Joo; Lee, Won Koo; Sim, Taebo |
2012-10-31 | Stereoselective total synthesis of the E-isomer of putative lucentamycin A | Selim, Khalid B.; Lee, Baeck Kyoung; Sim, Taebo |
2018-09 | Structural and Atropisomeric Factors Governing the Selectivity of Pyrimido-benzodiazipinones as Inhibitors of Kinases and Bromodomains | Wang, Jinhua; Erazo, Tatiana; Ferguson, Fleur M.; Buckley, Dennis L.; Gomez, Nestor; Munoz-Guardiola, Pau; Dieguez-Martinez, Nora; Deng, Xianming; Hao, Mingfeng; Massefski, Walter; Fedorov, Oleg; Offei-Addo, Nana Kwaku; Park, Paul M.; Dai, Lingling; DiBona, Amy; Becht, Kelly; Kim, Nam Doo; McKeown, Michael R.; Roberts, Justin M.; Zhang, Jinwei; Sim, Taebo; Alessi, Dario R.; Bradner, James E.; Lizcano, Jose M.; Blacklow, Stephen C.; Qi, Jun; Xu, Xiang; Gray, Nathanael S. |
2013-12 | Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-ones | Deng, Xianming; Elkins, Jonathan M.; Zhang, Jinwei; Yang, Qingkai; Erazo, Tatiana; Gomez, Nestor; Choi, Hwan Geun; Wang, Jinhua; Dzamko, Nicolas; Lee, Jiing-Dwan; Sim, Taebo; Kim, NamDoo; Alessi, Dario R.; Lizcano, Jose M.; Knapp, Stefan; Gray, Nathanael S. |
2017-12 | Structural Revision of Baulamycin A and Structure-Activity Relationships of Baulamycin A Derivatives | Sengupta, Sandip; Bae, Munhyung; Oh, Dong-Chan; Dash, Uttam; Kim, Hak Joong; Song, Woon Young; Shin, Injae; Sim, Taebo |
2012-09 | Structure Assignment of Lucentamycin E and Revision of the Olefin Geometries of the Marine-Derived Lucentamycins | Cha, Jin Wook; Park, Jin-Soo; Sim, Taebo; Nam, Sang-Jip; Kwon, Hak Cheol; Del Valle, Juan R.; Fenical, William |
2011-03-15 | Structure based design and syntheses of amino-1H-pyrazole amide derivatives as selective Raf kinase inhibitors in melanoma cells | Kim, Mi-hyun; Kim, Minjung; Yu, Hana; Kim, Hwan; Yoo, Kyung Ho; Sim, Taebo; Hah, Jung-Mi |
2014-08-01 | Structure-based optimization and biological evaluation of trisubstituted pyrazole as a core structure of potent ROS1 kinase inhibitors | Park, Byung Sun; Al-Sanea, Mohammad M.; Abdelazem, Ahmed Z.; Park, Hye Mi; Roh, Eun Joo; Park, Hyun-Mee; Yoo, Kyung Ho; Sim, Taebo; Tae, Jin Sung; Lee, So Ha |
2020-12 | Suppression of TRPM7 enhances TRAIL-induced apoptosis in triple-negative breast cancer cells | Song, Chiman; Choi, Seunghye; Oh, Ki-Bong; Sim, Taebo |
2011-04-20 | Synthesis and Antiproliferative Activity of Pyridinylcarbonylpyrimidines Against Melanoma Cell Line | Ahn, Hyemi; Lee, Jun A.; Kim, Hwan; Oh, Chang-Hyun; Lee, So Ha; Sim, Taebo; Hah, Jung-Mi; Kim, Dong Jin; Yoo, Kyung Ho |
2015-01-27 | Synthesis and biological evaluation of new pyrazol-4-ylpyrimidine derivatives as potential ROS1 kinase inhibitors | Abdelazem, Ahmed Z.; Al-Sanea, Mohammad M.; Park, Byung Sun; Park, Hye Mi; Yoo, Kyung Ho; Sim, Taebo; Park, Jong Bae; Lee, Seung-Hoon; Lee, So Ha |
2013-10-15 | Synthesis and biological evaluation of novel 3,4-diaryl lactam derivatives as triple reuptake inhibitors | Park, Jung-eun; Song, Chiman; Choi, Keehyun; Sim, Taebo; Moon, Bongjin; Roh, Eun Joo |
2019-08 | Synthesis and structure activity relationships of a series of 4-amino-1H-pyrazoles as covalent inhibitors of CDK14 | Ferguson, Fleur M.; Doctor, Zainab M.; Ficarro, Scott B.; Marto, Jarrod A.; Kim, Nam Doo; Sim, Taebo; Gray, Nathanael S. |
2016-10 | Synthesis of novel arylaminoquinazolinylurea derivatives and their antiproliferative activities against bladder cancer cell line | Kim, Jung Hun; Kwak, Yeonui; Song, Chiman; Roh, Eun Joo; Oh, Chang-Hyun; Lee, So Ha; Sim, Taebo; Choi, Jung Hoon; Yoo, Kyung Ho |
2015-08 | Synthesis of quinolinylaminopyrimidines and quinazolinylmethylaminopyrimidines with antiproliferative activity against melanoma cell line | Lee, Jun A.; Roh, Eun Joo; Oh, Chang-Hyun; Lee, So Ha; Sim, Taebo; Kim, Jong Seung; Yoo, Kyung Ho |
2010-01-28 | Targeting Bcr-Abl by combining allosteric with ATP-binding-site inhibitors | Zhang, Jianming; Adrian, Francisco J.; Jahnke, Wolfgang; Cowan-Jacob, Sandra W.; Li, Allen G.; Iacob, Roxana E.; Sim, Taebo; Powers, John; Dierks, Christine; Sun, Fangxian; Guo, Gui-Rong; Ding, Qiang; Okram, Barun; Choi, Yongmun; Wojciechowski, Amy; Deng, Xianming; Liu, Guoxun; Fendrich, Gabriele; Strauss, Andre; Vajpai, Navratna; Grzesiek, Stephan; Tuntland, Tove; Liu, Yi; Bursulaya, Badry; Azam, Mohammad; Manley, Paul W.; Engen, John R.; Daley, George Q.; Warmuth, Markus; Gray, Nathanael S. |