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Showing results 17 to 30 of 30

Issue DateTitleAuthor(s)
2017-12-01Novel LCK/FMS inhibitors based on phenoxypyrimidine scaffold as potential treatment for inflammatory disordersFarag, Ahmed Karam; Elkamhawy, Ahmed; Londhe, Ashwini M.; Lee, Kyung-Tae; Pae, Ae Nim; Roh, Eun Joo
2014-09-12Novel quinazoline-urea analogues as modulators for A beta-induced mitochondrial dysfunction: Design, synthesis, and molecular docking studyElkamhawy, Ahmed; Lee, Jiyoun; Park, Beoung-Geon; Park, Insun; Pae, Ae Nim; Roh, Eun Joo
2023-05Novel topoisomerase II/EGFR dual inhibitors: design, synthesis and docking studies of naphtho[2',3':4,5]thiazolo[3,2-a]pyrimidine hybrids as potential anticancer agents with apoptosis inducing activityMourad, Mai A. E.; Elmaaty, Ayman Abo; Zaki, Islam; Mourad, Ahmed A. E.; Hofni, Amal; Khodir, Ahmed E.; Aboubakr, Esam M.; Elkamhawy, Ahmed; Roh, Eun Joo; Al-Karmalawy, Ahmed A.
2019-11Optimization study towards more potent thiazolidine-2,4-dione IKK-beta modulator: Synthesis, biological evaluation and in silico docking simulationElkamhawy, Ahmed; Kim, Nam Youn; Hassan, Ahmed H. E.; Park, Jung-eun; Yang, Jeong-Eun; Elsherbeny, Mohamed H.; Paik, Sora; Oh, Kwang-Seok; Lee, Byung Ho; Lee, Mi Young; Shin, Kye Jung; Pae, Ae Nim; Lee, Kyung-Tae; Roh, Eun Joo
2018-09-05Pyrazinyl ureas revisited: 1-(3-(Benzyloxy)pyrazin-2-yl)-3-(3,4-dichlorophenyl)urea, a new blocker of A beta-induced mPTP opening for Alzheimer's diseaseElkamhawy, Ahmed; Park, Jung-eun; Hassan, Ahmed H. E.; Pae, Ae Nim; Lee, Jiyoun; Paik, Sora; Park, Beoung-Geon; Roh, Eun Joo
2018-05-10Repositioning of the antipsychotic trifluoperazine: Synthesis, biological evaluation and in silico study of trifluoperazine analogs as anti-glioblastoma agentsKang, Seokmin; Lee, Jung Moo; Jeon, Borami; Elkamhawy, Ahmed; Paik, Sora; Hong, Jinpyo; Oh, Soo-Jin; Paek, Sun Ha; Lee, C. Justin; Hassan, Ahmed H. E.; Kang, Sang Soo; Roh, Eun Joo
2021-09Scaffold Repurposing of In-House Small Molecule Candidates Leads to Discovery of First-in-Class CDK-1/HER-2 Dual Inhibitors: In Vitro and In Silico ScreeningElkamhawy, Ahmed; Ammar, Usama M.; Paik, Sora; Abdellattif, Magda H.; Elsherbeny, Mohamed H.; Lee, Kyeong; Roh, Eun Joo
2020-07Sulfonamide-based 4-anilinoquinoline derivatives as novel dual Aurora kinase (AURKA/B) inhibitors: Synthesis, biological evaluation and in silico insightsAl-Sanea, Mohammad M.; Elkamhawy, Ahmed; Paik, Sora; Lee, Kyeong; El Kerdawy, Ahmed M.; Abbas, Bukhari Syed Nasir; Roh, Eun Joo; Eldehna, Wagdy M.; Elshemy, Heba A. H.; Bakr, Rania B.; Farahat, Ibrahim Ali; Alzarea, Abdulaziz, I; Alzarea, Sami, I; Alharbi, Khalid S.; Abdelgawad, Mohamed A.
2019-01-01Synthesis and biological evaluation of novel 3-(quinolin-4-ylamino)benzenesulfonamidesAQ3 as carbonic anhydrase isoforms I and II inhibitorsAl-Sanea, Mohammad M.; Elkamhawy, Ahmed; Paik, Sora; Bua, Silvia; Lee, So Ha; Abdelgawad, Mohamed A.; Roh, Eun Joo; Eldehna, Wagdy M.; Supuran, Claudiu T.
2018-01-20Synthesis and evaluation of 2-(3-arylureido)pyridines and 2-(3-arylureido)pyrazines as potential modulators of A beta-induced mitochondrial dysfunction in Alzheimer's diseaseElkamhawy, Ahmed; Park, Jung-eun; Hassan, Ahmed H. E.; Pae, Ae Nim; Lee, Jiyoun; Park, Beoung-Geon; Roh, Eun Joo
2017-12-01Synthesis and evaluation of new pyridyl/pyrazinyl thiourea derivatives: Neuroprotection against amyloid-beta-induced toxicityPark, Jung-eun; Elkamhawy, Ahmed; Hassan, Ahmed H. E.; Pae, Ae Nim; Lee, Jiyoun; Paik, Sora; Park, Beoung-Geon; Roh, Eun Joo
2015-01Synthesis and in Vitro Screening of Phenylbipyridinylpyrazole Derivatives as Potential Antiproliferative AgentsAl-Sanea, Mohammad M.; Elkamhawy, Ahmed; Zakaria, Ahmed; Park, Byung Sun; Kwon, Youngjoo; Lee, So Ha; Lee, Sang Woo; Kim, In Tae
2015-11-15Targeting EGFR/HER2 tyrosine kinases with a new potent series of 6-substituted 4-anilinoquinazoline hybrids: Design, synthesis, kinase assay, cell-based assay, and molecular dockingElkamhawy, Ahmed; Farag, Ahmed Karam; Viswanath, Ambily Nath Indu; Bedair, Tarek M.; Leem, Dong Gyu; Lee, Kyung-Tae; Pae, Ae Nim; Roh, Eun Joo
2020-02-15Thiazolidine-2,4-dione-based irreversible allosteric IKK-beta kinase inhibitors: Optimization into in vivo active anti-inflammatory agentsElkamhawy, Ahmed; Kim, Nam Youn; Hassan, Ahmed H. E.; Park, Jung-eun; Paik, Sora; Yang, Jeong-Eun; Oh, Kwang-Seok; Lee, Byung Ho; Lee, Mi Young; Shin, Kye Jung; Pae, Ae Nim; Lee, Kyung-Tae; Roh, Eun Joo
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