Showing results 59 to 88 of 89
Issue Date | Title | Author(s) |
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2021-11-11 | Optimization and Evaluation of Novel Antifungal Agents for the Treatment of Fungal Infection | Choi, Ji Won; Lee, Kyung-Tae; Kim, Siwon; Lee, Ye Rim; Kim, Hyeon Ji; Seo, Kyung Jin; Lee, Myung Ha; Yeon, Seul Ki; Jang, Bo Ko; Park, Sun Jun; Kim, Hyeon Jeong; Park, Jong-Hyun; Kim, Dahee; Lee, Dong-Gi; Cheong, Eunji; Lee, Jong-Seung; Bahn, Yong-Sun; Park, Ki Duk |
2023-08 | Optimization and evaluation of pyridinyl vinyl sulfones as Nrf2 activator for the antioxidant and anti-inflammatory effects | Kim, Byungeun; Kim, Rium; Kim, Hyeon Jeong; Kim, Yoowon; Park, Sun Jun; Lee, Elijah Hwejin; Kim, Jushin; Kim, Jaehwan; Choi, Ji Won; Park, Jong-Hyun; Park, Ki Duk |
2019-01 | Optimization of Vinyl Sulfone Derivatives as Potent Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Activators for Parkinson's Disease Therapy | Choi, Ji Won; Kim, Siwon; Park, Jong-Hyun; Kim, Hyeon Jeong; Shin, Su Jeon; Kim, Jin Woo; Woo, Seo Yeon; Lee, Changho; Han, Sang Moon; Lee, Jaeick; Pae, Ae Nim; Han, Gyoonhee; Park, Ki Duk |
2013-09-01 | Oxazolopyridines and thiazolopyridines as monoamine oxidase B inhibitors for the treatment of Parkinson's disease | Park, Hye Ri; Kim, Jiyoon; Kim, Taekeun; Jo, Seonmi; Yeom, Miyoung; Moon, Bongjin; Choo, Il Han; Lee, Jaeick; Lim, Eun Jeong; Park, Ki Duk; Min, Sun-Joon; Nam, Ghilsoo; Keum, Gyochang; Lee, C. Justin; Choo, Hyunah |
2019-07 | Phosphorylated CRMP2 Regulates Spinal Nociceptive Neurotransmission | Yu, Jie; Moutal, Aubin; Dorame, Angie; Bellampalli, Shreya S.; Chefdeville, Aude; Kanazawa, Iori; Pham, Nancy Y. N.; Park, Ki Duk; Weimer, Jill M.; Khanna, Rajesh |
2022-12 | Positional scanning of natural product hispidol's ring-B: discovery of highly selective human monoamine oxidase-B inhibitor analogues downregulating neuroinflammation for management of neurodegenerative diseases | Hassan, Ahmed H. E.; Kim, Hyeon Jeong; Gee, Min Sung; Park, Jong-Hyun; Jeon, Hye Rim; Lee, Cheol Jung; Choi, Yeonwoo; Moon, Suyeon; Lee, Danbi; Lee, Jong Kil; Park, Ki Duk; Lee, Yong Sup |
2020-06-17 | PyrPeg, a Blood-Brain-Barrier-Penetrating Two-Photon Imaging Probe, Selectively Detects Neuritic Plaques, Not Tau Aggregates | Choi, Ji-Woo; Ju, Yeon Ha; Choi, Yunsook; Hyeon, Seung Jae; Gadhe, Changdev G.; Park, Jong-Hyun; Kim, Mun Seok; Baek, Seungyeop; Kim, YoungSoo; Park, Ki Duk; Pae, Ae Nim; Ryu, Hoon; Lee, C. Justin; Cho, Bong Rae |
2016-02 | Relationship between chromatographic resolution and amide structure of chiral 2-hydroxy acids as O-(-)-menthoxycarbonylated diastereomeric derivatives for enantiomeric separation on achiral gas chromatography | Cha, Eunju; Kim, Sohee; Lee, Kang Mi; Kim, Ho Jun; Kim, Ki Hun; Kwon, Oh-Seung; Park, Ki Duk; Lee, Jaeick |
2020-01-01 | Reprofiling of pyrimidine-based DAPK1/CSF1R dual inhibitors: identification of 2,5-diamino-4-pyrimidinol derivatives as novel potential anticancer lead compounds | Farag, Ahmed K.; Hassan, Ahmed H. E.; Ahn, Byung Sun; Park, Ki Duk; Roh, Eun Joo |
2016-04 | (S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5 | Moutal, Aubin; Francois-Moutal, Liberty; Perez-Miller, Samantha; Cottier, Karissa; Chew, Lindsey Anne; Yeon, Seul Ki; Dai, Jixun; Park, Ki Duk; Khanna, May; Khanna, Rajesh |
2016-07 | (S)-lacosamide inhibition of CRMP2 phosphorylation reduces postoperative and neuropathic pain behaviors through distinct classes of sensory neurons identified by constellation pharmacology | Moutal, Aubin; Chew, Lindsey A.; Yang, Xiaofang; Wang, Yue; Yeon, Seul Ki; Telemi, Edwin; Meroueh, Seeneen; Park, Ki Duk; Shrinivasan, Raghuraman; Gilbraith, Kerry B.; Qu, Chaoling; Xie, Jennifer Y.; Patwardhan, Amol; Vanderah, Todd W.; Khanna, May; Porreca, Frank; Khanna, Rajesh |
2016-02-17 | Screening, Synthesis, and In Vitro Evaluation of Vinyl Sulfones as Inhibitors of Complement-Dependent Cytotoxicity in Neuromyelitis Optica | Ju, Eun Ji; Yeon, Seul Ki; Park, Jong-Hyun; Cheon, So Young; Choi, Ji Won; Ha, Taehwan; Jang, Bo Ko; Kim, Siwon; Kang, Yong Gu; Hwang, Hayoung; Cho, Sung Jin; Cheong, Eunji; Bahn, Yong Sun; Pae, Ae Nim; Kim, Sung Min; Park, Ki Duk |
2020-12 | Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer's disease via H2O2- production | Chun, Heejung; Im, Hyeonjoo; Kang, You Jung; Kim, Yunha; Shin, Jin Hee; Won, Woojin; Lim, Jiwoon; Ju, Yeonha; Park, Yongmin Mason; Kim, Sunpil; Lee, Seung Eun; Lee, Jaekwang; Woo, Junsung; Hwang, Yujin; Cho, Hyesun; Jo, Seonmi; Park, Jong-Hyun; Kim, Daesoo; Kim, Doo Yeon; Seo, Jeong-Sun; Gwag, Byoung Joo; Kim, Young Soo; Park, Ki Duk; Kaang, Bong-Kiun; Cho, Hansang; Ryu, Hoon; Lee, C. Justin |
2014-07-24 | Substituted N-(Biphenyl-4 '-yl)methyl (R)-2-Acetamido-3-methoxypropionamides: Potent Anticonvulsants That Affect Frequency (Use) Dependence and Slow Inactivation of Sodium Channels | Lee, Hyosung; Park, Ki Duk; Torregrosa, Robert; Yang, Xiao-Fang; Dustrude, Erik T.; Wang, Yuying; Wilson, Sarah M.; Barbosa, Cindy; Xiao, Yucheng; Cummins, Theodore R.; Khanna, Rajesh; Kohn, Harold |
2016-08-20 | Synthesis & optimization of vinyl sulfone compounds as Nrf2 activator | Choi, Ji Won; Park, Jong Hyun; Ha, Tae Hwan; Yeon, Seul Ki; Park, Ki Duk; Kim, Si Won; Lee, Ye Rim; Shin, Su Jeong; Jang, Bo Ko |
2023-05 | Synthesis and Biological Evaluation of O-6-Aminoalkyl-Hispidol Analogs as Multifunctional Monoamine Oxidase-B Inhibitors towards Management of Neurodegenerative Diseases | Hassan, Ahmed H. E.; Kim, Hyeon Jeong; Park, Keontae; Choi, Yeonwoo; Moon, Suyeon; Lee, Chae Hyeon; Kim, Yeon Ju; Cho, Soo Bin; Gee, Min Sung; Lee, Danbi; Park, Jong-Hyun; Lee, Jong Kil; Ryu, Jong Hoon; Park, Ki Duk; Lee, Yong Sup |
2016-01-01 | Synthesis and biological evaluation of picolinamides and thiazole-2-carboxamides as mGluR5 (metabotropic glutamate receptor 5) antagonists | Hoang Nam Vu; Kim, Ji Young; Hassan, Ahmed H. E.; Choi, Kihang; Park, Jong-Hyun; Park, Ki Duk; Lee, Jae Kyun; Pae, Ae Nim; Choo, Hyunah; Min, Sun-Joon; Cho, Yong Seo |
2018-11-01 | Synthesis and Development of Novel Compounds Selectively Targeting on Sphingosine 1-Phosphate Receptor 1 (S1P1) for Treatment of Multiple Sclerosis | Yeon, Seul Ki; Park, Jong-Hyun; Park, Ki Duk; Kim, Hyeon Jeong; Shin, Su Jeong |
2016-08-20 | Synthesis and development of novel compounds selectively targeting on sphingosine 1-phosphate receptor 1 (S1P1) for treatment of multiple sclerosis | Yeon, Seul Ki; Park, Jong Hyun; Ha, Tae Hwan; Choi, Ji Won; Park, Ki Duk; Kim, Si Won; Lee, Ye Rim; Shin, Su Jeong; Jang, Bo Ko |
2018-01-01 | Synthesis and evaluation of biaryl derivatives for structural characterization of selective monoamine oxidase B inhibitors toward Parkinson's disease therapy | Yeon, Seul Ki; Choi, Ji Won; Park, Jong-Hyun; Lee, Ye Rim; Kim, Hyeon Jeong; Shin, Su Jeong; Jang, Bo Ko; Kim, Siwon; Bahn, Yong-Sun; Han, Gyoonhee; Lee, Yong Sup; Pae, Ae Nim; Park, Ki Duk |
2022-05 | Synthesis and Evaluation of Serinolamide Derivatives as Sphingosine-1-Phosphate-1 (S1P(1)) Receptor Agonists | Park, Sun Jun; Kim, Jushin; Kim, Jaehwan; Kim, Yoowon; Lee, Elijah Hwejin; Kim, Hyeon Jeong; Kim, Siwon; Kim, Byungeun; Kim, Rium; Choi, Ji Won; Park, Jong-Hyun; Park, Ki Duk |
2015-10 | Synthesis of a series of unsaturated ketone derivatives as selective and reversible monoamine oxidase inhibitors | Choi, Ji Won; Jang, Bo Ko; Cho, Nam-chul; Park, Jong-Hyun; Yeon, Seul Ki; Ju, Eun Ji; Lee, Yong Sup; Han, Gyoonhee; Pae, Ae Nim; Kim, Dong Jin; Park, Ki Duk |
2015-03 | Synthesis of Novel Dihydropyridothienopyrimidin-4,9-dione Derivatives | Kim, Youngjae; Kim, Minjoo; Park, Mooseong; Tae, Jinsung; Baek, Du-Jong; Park, Ki Duk; Choo, Hyunah |
2018-10-01 | Synthesis of oxidative metabolites of CRA13 and their analogs: Identification of CRA13 active metabolites and analogs thereof with selective CB2R affinity | Hassan, Ahmed H. E.; Cho, Min Chang; Kim, Hye In; Yang, Ji Seul; Park, Kyung Tae; Hwang, Ji Young; Jang, Choon-Gon; Park, Ki Duk; Lee, Yong Sup |
2019-07 | Targeting the CaV alpha-CaV beta interaction yields an antagonist of the N-type CaV2.2 channel with broad antinociceptive efficacy | Khanna, Rajesh; Yu, Jie; Yang, Xiaofang; Moutal, Aubin; Chefdeville, Aude; Gokhale, Vijay; Shuja, Zunaira; Chew, Lindsey A.; Bellampalli, Shreya S.; Luo, Shizhen; Francois-Moutal, Liberty; Serafini, Maria J.; Ha, Taehwan; Perez-Miller, Samantha; Park, Ki Duk; Patwardhan, Amol M.; Streicher, John M.; Colecraf, Henry M.; Khanna, May |
2022-04 | The novel antifungal agent AB-22 displays in vitro activity against hyphal growth and biofilm formation in Candida albicans and potency for treating systemic candidiasis | Lee, Kyung-Tae; Lee, Dong-Gi; Choi, Ji Won; Park, Jong-Hyun; Park, Ki Duk; Lee, Jong-Seung; Bahn, Yong-Sun |
2018-10 | The Novel Neuroprotective Compound KMS99220 Has an Early Anti-neuroinflammatory Effect via AMPK and HO-1, Independent of Nrf2 | Lee, Ji Ae; Kim, Hye Ri; Kim, Jiyoung; Park, Ki Duk; Kim, Dong Jin; Hwang, Onyou |
2024-05 | The role of astrocytic γ-aminobutyric acid in the action of inhalational anesthetics | Won, Dongwook; Lee, Elliot H.; Chang, Jee-Eun; Nam, Min-Ho; Park, Ki Duk; Oh, Soo-Jin; Hwang, Jin-Young |
2023-10 | Two weeks dose range-finding and four weeks repeated dose oral toxicity study of a novel reversible monoamine oxidase B inhibitor KDS2010 in cynomolgus monkeys | Kim, Kyung-Tai; Cho, Doo-Wan; Cho, Jae-woo; Im, Wan-Jung; Kim, Da-Hee; Park, Jong-Hyun; Park, Ki Duk; Yang, Young-Su; Han, Su-Cheol |
2024-05 | Visualizing cancer-originating acetate uptake through monocarboxylate transporter 1 in reactive astrocytes in the glioblastoma tumor microenvironment | Kim, Dongwoo; Ko, Hae Young; Chung, Jee-In; Park, Yongmin Mason; Lee, Sangwon; Kim, Seon Yoo; Kim, Jisu; Chun, Joong-Hyun; Han, Kyung-Seok; Lee, Misu; Ju, Yeon Ha; Park, Sun Jun; Park, Ki Duk; Nam, Min-Ho; Kim, Se Hoon; Shim, Jin-Kyoung; Park, Youngjoo; Lim, Hyunkeong; Park, Jaekyung; Lee, Gwan-Ho; Kim, Hyunjin; Kim, Suhyun; Park, Uiyeol; Ryu, Hoon; Lee, So Yun; Park, Sunghyouk; Kang, Seok-Gu; Chang, Jong Hee; Lee, C. Justin; Yun, Mijin |