Browsing byAuthorPark, Ki Duk

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Showing results 63 to 89 of 89

Issue DateTitleAuthor(s)
2019-07Phosphorylated CRMP2 Regulates Spinal Nociceptive NeurotransmissionYu, Jie; Moutal, Aubin; Dorame, Angie; Bellampalli, Shreya S.; Chefdeville, Aude; Kanazawa, Iori; Pham, Nancy Y. N.; Park, Ki Duk; Weimer, Jill M.; Khanna, Rajesh
2022-12Positional scanning of natural product hispidol's ring-B: discovery of highly selective human monoamine oxidase-B inhibitor analogues downregulating neuroinflammation for management of neurodegenerative diseasesHassan, Ahmed H. E.; Kim, Hyeon Jeong; Gee, Min Sung; Park, Jong-Hyun; Jeon, Hye Rim; Lee, Cheol Jung; Choi, Yeonwoo; Moon, Suyeon; Lee, Danbi; Lee, Jong Kil; Park, Ki Duk; Lee, Yong Sup
2020-06-17PyrPeg, a Blood-Brain-Barrier-Penetrating Two-Photon Imaging Probe, Selectively Detects Neuritic Plaques, Not Tau AggregatesChoi, Ji-Woo; Ju, Yeon Ha; Choi, Yunsook; Hyeon, Seung Jae; Gadhe, Changdev G.; Park, Jong-Hyun; Kim, Mun Seok; Baek, Seungyeop; Kim, YoungSoo; Park, Ki Duk; Pae, Ae Nim; Ryu, Hoon; Lee, C. Justin; Cho, Bong Rae
2016-02Relationship between chromatographic resolution and amide structure of chiral 2-hydroxy acids as O-(-)-menthoxycarbonylated diastereomeric derivatives for enantiomeric separation on achiral gas chromatographyCha, Eunju; Kim, Sohee; Lee, Kang Mi; Kim, Ho Jun; Kim, Ki Hun; Kwon, Oh-Seung; Park, Ki Duk; Lee, Jaeick
2020-01-01Reprofiling of pyrimidine-based DAPK1/CSF1R dual inhibitors: identification of 2,5-diamino-4-pyrimidinol derivatives as novel potential anticancer lead compoundsFarag, Ahmed K.; Hassan, Ahmed H. E.; Ahn, Byung Sun; Park, Ki Duk; Roh, Eun Joo
2016-04(S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5Moutal, Aubin; Francois-Moutal, Liberty; Perez-Miller, Samantha; Cottier, Karissa; Chew, Lindsey Anne; Yeon, Seul Ki; Dai, Jixun; Park, Ki Duk; Khanna, May; Khanna, Rajesh
2016-07(S)-lacosamide inhibition of CRMP2 phosphorylation reduces postoperative and neuropathic pain behaviors through distinct classes of sensory neurons identified by constellation pharmacologyMoutal, Aubin; Chew, Lindsey A.; Yang, Xiaofang; Wang, Yue; Yeon, Seul Ki; Telemi, Edwin; Meroueh, Seeneen; Park, Ki Duk; Shrinivasan, Raghuraman; Gilbraith, Kerry B.; Qu, Chaoling; Xie, Jennifer Y.; Patwardhan, Amol; Vanderah, Todd W.; Khanna, May; Porreca, Frank; Khanna, Rajesh
2016-02-17Screening, Synthesis, and In Vitro Evaluation of Vinyl Sulfones as Inhibitors of Complement-Dependent Cytotoxicity in Neuromyelitis OpticaJu, Eun Ji; Yeon, Seul Ki; Park, Jong-Hyun; Cheon, So Young; Choi, Ji Won; Ha, Taehwan; Jang, Bo Ko; Kim, Siwon; Kang, Yong Gu; Hwang, Hayoung; Cho, Sung Jin; Cheong, Eunji; Bahn, Yong Sun; Pae, Ae Nim; Kim, Sung Min; Park, Ki Duk
2020-12Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer's disease via H2O2- productionChun, Heejung; Im, Hyeonjoo; Kang, You Jung; Kim, Yunha; Shin, Jin Hee; Won, Woojin; Lim, Jiwoon; Ju, Yeonha; Park, Yongmin Mason; Kim, Sunpil; Lee, Seung Eun; Lee, Jaekwang; Woo, Junsung; Hwang, Yujin; Cho, Hyesun; Jo, Seonmi; Park, Jong-Hyun; Kim, Daesoo; Kim, Doo Yeon; Seo, Jeong-Sun; Gwag, Byoung Joo; Kim, Young Soo; Park, Ki Duk; Kaang, Bong-Kiun; Cho, Hansang; Ryu, Hoon; Lee, C. Justin
2014-07-24Substituted N-(Biphenyl-4 '-yl)methyl (R)-2-Acetamido-3-methoxypropionamides: Potent Anticonvulsants That Affect Frequency (Use) Dependence and Slow Inactivation of Sodium ChannelsLee, Hyosung; Park, Ki Duk; Torregrosa, Robert; Yang, Xiao-Fang; Dustrude, Erik T.; Wang, Yuying; Wilson, Sarah M.; Barbosa, Cindy; Xiao, Yucheng; Cummins, Theodore R.; Khanna, Rajesh; Kohn, Harold
2016-08-20Synthesis & optimization of vinyl sulfone compounds as Nrf2 activatorChoi, Ji Won; Park, Jong Hyun; Ha, Tae Hwan; Yeon, Seul Ki; Park, Ki Duk; Kim, Si Won; Lee, Ye Rim; Shin, Su Jeong; Jang, Bo Ko
2023-05Synthesis and Biological Evaluation of O-6-Aminoalkyl-Hispidol Analogs as Multifunctional Monoamine Oxidase-B Inhibitors towards Management of Neurodegenerative DiseasesHassan, Ahmed H. E.; Kim, Hyeon Jeong; Park, Keontae; Choi, Yeonwoo; Moon, Suyeon; Lee, Chae Hyeon; Kim, Yeon Ju; Cho, Soo Bin; Gee, Min Sung; Lee, Danbi; Park, Jong-Hyun; Lee, Jong Kil; Ryu, Jong Hoon; Park, Ki Duk; Lee, Yong Sup
2016-01-01Synthesis and biological evaluation of picolinamides and thiazole-2-carboxamides as mGluR5 (metabotropic glutamate receptor 5) antagonistsHoang Nam Vu; Kim, Ji Young; Hassan, Ahmed H. E.; Choi, Kihang; Park, Jong-Hyun; Park, Ki Duk; Lee, Jae Kyun; Pae, Ae Nim; Choo, Hyunah; Min, Sun-Joon; Cho, Yong Seo
2018-11-01Synthesis and Development of Novel Compounds Selectively Targeting on Sphingosine 1-Phosphate Receptor 1 (S1P1) for Treatment of Multiple SclerosisYeon, Seul Ki; Park, Jong-Hyun; Park, Ki Duk; Kim, Hyeon Jeong; Shin, Su Jeong
2016-08-20Synthesis and development of novel compounds selectively targeting on sphingosine 1-phosphate receptor 1 (S1P1) for treatment of multiple sclerosisYeon, Seul Ki; Park, Jong Hyun; Ha, Tae Hwan; Choi, Ji Won; Park, Ki Duk; Kim, Si Won; Lee, Ye Rim; Shin, Su Jeong; Jang, Bo Ko
2018-01-01Synthesis and evaluation of biaryl derivatives for structural characterization of selective monoamine oxidase B inhibitors toward Parkinson's disease therapyYeon, Seul Ki; Choi, Ji Won; Park, Jong-Hyun; Lee, Ye Rim; Kim, Hyeon Jeong; Shin, Su Jeong; Jang, Bo Ko; Kim, Siwon; Bahn, Yong-Sun; Han, Gyoonhee; Lee, Yong Sup; Pae, Ae Nim; Park, Ki Duk
2022-05Synthesis and Evaluation of Serinolamide Derivatives as Sphingosine-1-Phosphate-1 (S1P(1)) Receptor AgonistsPark, Sun Jun; Kim, Jushin; Kim, Jaehwan; Kim, Yoowon; Lee, Elijah Hwejin; Kim, Hyeon Jeong; Kim, Siwon; Kim, Byungeun; Kim, Rium; Choi, Ji Won; Park, Jong-Hyun; Park, Ki Duk
2015-10Synthesis of a series of unsaturated ketone derivatives as selective and reversible monoamine oxidase inhibitorsChoi, Ji Won; Jang, Bo Ko; Cho, Nam-chul; Park, Jong-Hyun; Yeon, Seul Ki; Ju, Eun Ji; Lee, Yong Sup; Han, Gyoonhee; Pae, Ae Nim; Kim, Dong Jin; Park, Ki Duk
2015-03Synthesis of Novel Dihydropyridothienopyrimidin-4,9-dione DerivativesKim, Youngjae; Kim, Minjoo; Park, Mooseong; Tae, Jinsung; Baek, Du-Jong; Park, Ki Duk; Choo, Hyunah
2018-10-01Synthesis of oxidative metabolites of CRA13 and their analogs: Identification of CRA13 active metabolites and analogs thereof with selective CB2R affinityHassan, Ahmed H. E.; Cho, Min Chang; Kim, Hye In; Yang, Ji Seul; Park, Kyung Tae; Hwang, Ji Young; Jang, Choon-Gon; Park, Ki Duk; Lee, Yong Sup
2019-07Targeting the CaV alpha-CaV beta interaction yields an antagonist of the N-type CaV2.2 channel with broad antinociceptive efficacyKhanna, Rajesh; Yu, Jie; Yang, Xiaofang; Moutal, Aubin; Chefdeville, Aude; Gokhale, Vijay; Shuja, Zunaira; Chew, Lindsey A.; Bellampalli, Shreya S.; Luo, Shizhen; Francois-Moutal, Liberty; Serafini, Maria J.; Ha, Taehwan; Perez-Miller, Samantha; Park, Ki Duk; Patwardhan, Amol M.; Streicher, John M.; Colecraf, Henry M.; Khanna, May
2022-04The novel antifungal agent AB-22 displays in vitro activity against hyphal growth and biofilm formation in Candida albicans and potency for treating systemic candidiasisLee, Kyung-Tae; Lee, Dong-Gi; Choi, Ji Won; Park, Jong-Hyun; Park, Ki Duk; Lee, Jong-Seung; Bahn, Yong-Sun
2018-10The Novel Neuroprotective Compound KMS99220 Has an Early Anti-neuroinflammatory Effect via AMPK and HO-1, Independent of Nrf2Lee, Ji Ae; Kim, Hye Ri; Kim, Jiyoung; Park, Ki Duk; Kim, Dong Jin; Hwang, Onyou
2024-05The role of astrocytic γ-aminobutyric acid in the action of inhalational anestheticsWon, Dongwook; Lee, Elliot H.; Chang, Jee-Eun; Nam, Min-Ho; Park, Ki Duk; Oh, Soo-Jin; Hwang, Jin-Young
2023-10Two weeks dose range-finding and four weeks repeated dose oral toxicity study of a novel reversible monoamine oxidase B inhibitor KDS2010 in cynomolgus monkeysKim, Kyung-Tai; Cho, Doo-Wan; Cho, Jae-woo; Im, Wan-Jung; Kim, Da-Hee; Park, Jong-Hyun; Park, Ki Duk; Yang, Young-Su; Han, Su-Cheol
2024-05Visualizing cancer-originating acetate uptake through monocarboxylate transporter 1 in reactive astrocytes in the glioblastoma tumor microenvironmentKim, Dongwoo; Ko, Hae Young; Chung, Jee-In; Park, Yongmin Mason; Lee, Sangwon; Kim, Seon Yoo; Kim, Jisu; Chun, Joong-Hyun; Han, Kyung-Seok; Lee, Misu; Ju, Yeon Ha; Park, Sun Jun; Park, Ki Duk; Nam, Min-Ho; Kim, Se Hoon; Shim, Jin-Kyoung; Park, Youngjoo; Lim, Hyunkeong; Park, Jaekyung; Lee, Gwan-Ho; Kim, Hyunjin; Kim, Suhyun; Park, Uiyeol; Ryu, Hoon; Lee, So Yun; Park, Sunghyouk; Kang, Seok-Gu; Chang, Jong Hee; Lee, C. Justin; Yun, Mijin
2023-07Visualizing reactive astrocyte-neuron interaction in Alzheimer’s disease using 11C-acetate and 18F-FDGNam, Min-Ho; Ko, Hae Young; Kim, Dongwoo; Lee, Sangwon; Park, Yongmin Mason; Hyeon, Seung Jae; Won, Woojin; Chung, Jee-In; Kim, Seon Yoo; Jo, Han Hee; Oh, Kyeong Taek; Han, Young-Eun; Lee, Gwan-Ho; Ju, Yeon Ha; Lee, Hyowon; Kim, Hyunjin; Heo, Jaejun; Bhalla, Mridula; Kim, Ki Jung; Kwon, Jea; Stein, Thor D.; Kong, Mingyu; Lee, Hyunbeom; Lee, Seung Eun; Oh, Soo-Jin; Chun, Joong-Hyun; Park, Mi-Ae; Park, Ki Duk; Ryu, Hoon; Yun, Mijin; Lee, C. Justin

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