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Showing results 39 to 68 of 88

Issue DateTitleAuthor(s)
2018-09-27First SAR Study for Overriding NRAS Mutant Driven Acute Myeloid LeukemiaCho, Hanna; Shin, Injae; Ju, Eunhye; Choi, Seunghye; Hur, Wooyoung; Kim, Haelee; Hong, Eunmi; Kim, Nam Doo; Choi, Hwan Geun; Gray, Nathanael S.; Sim, Taebo
2017-02-23Highly stereoselective synthesis of mupirocin HSengupta, Sandip; Kim, Hak Joong; Cho, Kyung Seon; Song, Woon Young; Sim, Taebo
2019-01-01Identification of 1H-pyrazolo[3,4-b]pyridine derivatives as potent ALK-L1196M inhibitorsNam, Yunju; Hwang, Dongkeun; Kim, Namdoo; Seo, Hong-Seog; Selim, Khalid B.; Sim, Taebo
2017-01-05Identification of a novel 5-amino-3-(5-cyclopropylisoxazol-3-yl)-1-isopropyl-1H-pyrazole-4-carboxa mide as a specific RET kinase inhibitorYoon, Hojong; Shin, Injae; Nam, Yunju; Kim, Nam Doo; Lee, Kyung-Bok; Sim, Taebo
2019-10-24Identification of a Unique Resorcylic Acid Lactone Derivative That Targets Both Lymphangiogenesis and AngiogenesisHan, Youngsun; Sengupta, Sandip; Lee, Byung Joo; Cho, Hanna; Kim, Jiknyeo; Choi, Hwan Geun; Dash, Uttam; Kim, Jin Hyoung; Kim, Nam Doo; Kim, Jeong Hun; Sim, Taebo
2017-01-01Identification of Existing Drugs That Effectively Target NTRK1 and ROS1 Rearrangements in Lung CancerChong, Curtis R.; Bahcall, Magda; Capelletti, Marzia; Kosaka, Takayuki; Ercan, Dalia; Sim, Taebo; Sholl, Lynette M.; Nishino, Mizuki; Johnson, Bruce E.; Gray, Nathanael S.; Janne, Pasi A.
2013-07-26Identification of methyl violet 2B as a novel blocker of focal adhesion kinase signaling pathway in cancer cellsKim, Hwan; Kim, Nam Doo; Lee, Jiyeon; Han, Gyoonhee; Sim, Taebo
2019-09-26Identification of Novel Resorcinol Amide Derivatives as Potent and Specific Pyruvate Dehydrogenase Kinase (PDHK) InhibitorsCho, Hanna; Shin, Injae; Cho, Kyungseon; Yoon, Hojong; Yoo, Eun Kyung; Kim, Mi-Jin; Park, Sungmi; Lee, In-Kyu; Kim, Nam Doo; Sim, Taebo
2015-05-14Identification of Novel ROS Inducers: Quinone Derivatives Tethered to Long Hydrocarbon ChainsHong, Yeonsun; Sengupta, Sandip; Hur, Wooyoung; Sim, Taebo
2015-05-14Identification of novel therapeutic targets in acute leukemias with NRAS mutations using a pharmacologic approachNonami, Atsushi; Sattler, Martin; Weisberg, Ellen; Liu, Qingsong; Zhang, Jianming; Patricelli, Matthew P.; Christie, Amanda L.; Saur, Amy M.; Kohl, Nancy E.; Kung, Andrew L.; Yoon, Hojong; Sim, Taebo; Gray, Nathanael S.; Griffin, James D.
2022-04Identification of Pyridinyltriazine Derivatives as Potent panFGFR Inhibitors against Gatekeeper Mutants for Overcoming Drug ResistanceRyu, SeongShick; Nam, Yunju; Kim, Namkyoung; Shin, Injae; Jeon, Eunhye; Kim, Younghoon; Kim, Nam Doo; Sim, Taebo
2017-04Identification of TG100-115 as a new and potent TRPM7 kinase inhibitor, which suppresses breast cancer cell migration and invasionSong, Chiman; Bae, Yeonju; Jun, JinJoo; Lee, Hyomin; Kim, Nam Doo; Lee, Kyung-Bok; Hur, Wooyoung; Park, Jae-Yong; Sim, Taebo
2017-02-23Identification of the First Selective Activin Receptor-Like Kinase 1 Inhibitor, a Reversible Version of L-783277Cho, Hanna; Sengupta, Sandip; Jeon, Sean S. H.; Hur, Wooyoung; Choi, Hwan Geun; Seo, Hong-Seog; Lee, Byung Joo; Kim, Jeong Hun; Chung, Minhwan; Jeon, Noo Li; Kim, Nam Doo; Sim, Taebo
2023-01Identification of Thiazolo[5,4-b]pyridine Derivatives as c-KIT Inhibitors for Overcoming Imatinib ResistanceNam, Yunju; Kim, Chan; Han, Junghee; Ryu Seong-Shick; Cho, Hanna; Song, Chiman; Kim, Nam Doo; Kim, Namkyoung; Sim, Taebo
2017-07In situ imaging of quantum dot-AZD4547 conjugates for tracking the dynamic behavior of fibroblast growth factor receptor 3Hwang, Gyoyeon; Kim, Hyeonhye; Yoon, Hojong; Song, Chiman; Lim, Dong-Kwon; Sim, Taebo; Lee, Jiyeon
2015-04In vitro metabolism of an estrogen-related receptor gamma modulator, GSK5182, by human liver microsomes and recombinant cytochrome P450sJoo, Jeongmin; Wu, Zhexue; Lee, Boram; Shon, Jong Cheol; Lee, Taeho; Lee, In-Kyu; Sim, Taebo; Kim, Kyung-Hee; Kim, Nam Doo; Kim, Seong Heon; Liu, Kwang-Hyeon
2013-09Inverse Agonist of Nuclear Receptor ERR gamma Mediates Antidiabetic Effect Through Inhibition of Hepatic GluconeogenesisKim, Don-Kyu; Gang, Gil-Tae; Ryu, Dongryeol; Koh, Minseob; Kim, Yo-Na; Kim, Su Sung; Park, Jinyoung; Kim, Yong-Hoon; Sim, Taebo; Lee, In-Kyu; Choi, Cheol Soo; Park, Seung Bum; Lee, Chul-Ho; Koo, Seung-Hoi; Choi, Hueng-Sik
2019-06Leveraging Compound Promiscuity to Identify Targetable Cysteines within the KinomeRao, Suman; Gurbani, Deepak; Du, Guangyan; Everley, Robert A.; Browne, Christopher M.; Chaikuad, Apirat; Tan, Li; Schroeder, Martin; Gondi, Sudershan; Ficarro, Scott B.; Sim, Taebo; Kim, Nam Doo; Berberich, Matthew J.; Knapp, Stefan; Marto, Jarrod A.; Westover, Kenneth D.; Sorger, Peter K.; Gray, Nathanael S.
2013-12New diarylamides and diarylureas possessing 8-amino(acetamido) quinoline scaffold: Synthesis, antiproliferative activities against melanoma cell lines, kinase inhibition, and in silico studiesKoh, Eun Jeong; El-Gamal, Mohammed I.; Oh, Chang-Hyun; Lee, So Ha; Sim, Taebo; Kim, Garam; Choi, Hong Seok; Hong, Jun Hee; Lee, Sang-gi; Yoo, Kyung Ho
2012-05-01New diarylureas and diarylamides possessing acet(benz)amidophenyl scaffold: Design, synthesis, and antiproliferative activity against melanoma cell lineKim, Hee Jin; Cho, Hye Jung; Kim, Hwan; El-Gamal, Mohammed I.; Oh, Chang-Hyun; Lee, So Ha; Sim, Taebo; Hah, Jung-Mi; Yoo, Kyung Ho
2015-06Non-receptor tyrosine kinase inhibitors enhances beta-cell survival by suppressing the PKC delta signal transduction pathway in streptozotocin - induced beta-cell apoptosisKarunakaran, Udayakumar; Park, Si Jun; Jun, Do Youn; Sim, Taebo; Park, Keun-Gyu; Kim, Myoung Ok; Lee, In Kyu
2013-07Novel Quinolinylaminoisoquinoline Bioisosteres of Sorafenib as Selective RAFI Kinase Inhibitors: Design, Synthesis, and Antiproliferative Activity against Melanoma Cell LineCho, Hye Jung; El-Gamal, Mohammed Ibrahim; Oh, Chang-Hyun; Lee, So Ha; Sim, Taebo; Kim, Garam; Choi, Hong Seok; Choi, Jung Hoon; Yoo, Kyung Ho
2012-03Novel small molecule Raf kinase inhibitors for targeted cancer therapeuticsKim, Do-Hee; Sim, Taebo
2015-03One step synthesis of quantum dot-magnetic nanoparticle heterodimers for dual modal imaging applicationsLee, Jiyeon; Hwang, Gyoyeon; Hong, Yeon Sun; Sim, Taebo
2015-01Optimization of Bipyridinyl Pyrazole Scaffolds via Design, Synthesis and Screening of a New Series of ROS1 Kinase-modulating CompoundsAl-Sanea, Mohammad M.; Park, Byung Sun; Abdelazem, Ahmed Z.; Selim, Khalid B.; Yoo, Kyung Ho; Sim, Taebo; Tae, Jin Sung; Lee, So Ha
2014-12Pharmacological targeting of the pseudokinase Her3Xie, Ting; Lim, Sang Min; Westover, Kenneth D.; Dodge, Michael E.; Ercan, Dalia; Ficarro, Scott B.; Udayakumar, Durga; Gurbani, Deepak; Tae, Hyun Seop; Riddle, Steven M.; Sim, Taebo; Marto, Jarrod A.; Jaenne, Pasi A.; Crews, Craig M.; Gray, Nathanael S.
2009-03Pharmacophore based 3D-QSAR study of VEGFR-2 inhibitorsNeaz, M. M.; Pasha, F. A.; Muddassar, M.; Lee, So Ha; Sim, Taebo; Hah, Jung-Mi; Cho, Seung Joo
2019-01Procaspase activating compound 1 controls tetracycline repressor-regulated gene expression systemSong, Chiman; Kim, Namkyoung; Park, Miri; Lee, Jiyeon; Oh, Ki-Bong; Sim, Taebo
2019-05Raman-Based in Situ Monitoring of Changes in Molecular Signatures during Mitochondrially Mediated ApoptosisShin, Hyeon Jeong; Lee, Ji Hye; Kim, Yong Duk; Shin, Injae; Sim, Taebo; Lim, Dong-Kwon
2012-02-18Rhodium-catalyzed reductive cyclization of 1,6-enynes and stereoselective synthesis of the putative structure of lucentamycin A and its stereoisomersHam, Young Jin; Yu, Hana; Kim, Nam Doo; Hah, Jung-Mi; Selim, Khalid B.; Choi, Hwan Geun; Sim, Taebo

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