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Showing results 1 to 28 of 28

Issue DateTitleAuthor(s)
2010-08A Type-II Kinase Inhibitor Capable of Inhibiting the T315I “Gatekeeper” Mutant of Bcr-Abl최환근; Pingda Ren; Francisco Adrian, et al
2010-09An efficient and enantioselective total synthesis of naturally occurring L-783277최환근; 손정범; 박동식, et al
2009-10An Efficient One-Pot Synthesis of Diastereomerically Pure 1,4-Dideoxy-1,4-Imino-D-Arabinitol from a chiral aziridine박동식; 최환근; 이원구, et al
2013-10An efficient synthesis of 1,4-dideoxy-1,4-imino-D- and L-arabinitol and 1,4-dideoxy-1,4-imino-D- and L-xylitol from chiral aziridines최환근; 박동식; 이원구, et al
2010-10An Efficient synthesis of 5-membered iminosugars and (-)-Swainsonine from Chiral Aziridines최환근; 이원구; 심태보
2008-10Asymetric 10-Membered Bislactam Synthesis for Peptidomimetic Template and Its Application to Kinase Inhibition심태보; 최환근; 손정범, et al
2018-11Brain injury induces HIF-1α-dependent transcriptional activation of LRRK2 that exacerbates brain damage류훈; 최환근; 배윤희, et al
2017-01Covalent Guanosine Mimetic Inhibitors of G12C KRAS심태보; 임상민; Yuan Xiong, et al
2012-08Development of ‘DFG-out’ inhibitors of gatekeeper mutant kinases최환근; Jianming Zhang; Ellen Weisberg, et al
2017-02Identification of the First Selective Activin Receptor-Like Kinase 1 Inhibitor, a Reversible Version of L-783277심태보; 허우영; 최환근, et al
2021-08Identification of Thieno[3,2-d]pyrimidine Derivatives as Dual Inhibitors of Focal Adhesion Kinase and FMS-like Tyrosine Kinase 3송치만; 류성식; 조한나, et al
2014-06In situ selectivity profiling and crystal structure of SML-8-73-1, an active site inhibitor of oncogenic K-Ras G12C임상민; John C. Hunter; Deepak Gurbani, et al
2012-02Rhodium-catalyzed reductive cyclization of 1,6-enynes and stereoselective synthesis of the putative structure of lucentamycin A and its stereoisomers함영진; 유하나; 김남두, et al
2013-02Stereoselective synthesis of (-)-8-epi-swainsonine starting with a chiral aziridine이백경; 최환근; 노은주, et al
2009-10The Chiral Synthesis of the Lucentamycins A-D Core, 3-Methyl -4-Ethylideneproline유하나; 최환근; 하정미, et al
2010-09The efficient one-step chlorination of methylsulfanyl group on pyrimidine ring system with sulfuryl chloride함영진; 이덕형; 최환근, et al
2014-01Therapeutic Targeting of Oncogenic K-Ras by a Covalent Catalytic Site Inhibitor심태보; 임상민; 최환근, et al
2009-06Total Synthesis of L-783277 and Biological Activity Evaluation of Its Derivatives on ERK최환근; 박동식; 손정범, et al
2009-09Total Synthesis of Natural Product, L-783277 and Biological Activity Evaluation of Its Derivatives최환근; 심태보
2010-04Total Synthesis of Putative Lucentamycin A and Its Analogues by Rh-Catalyzed Diastereoselective Cycloisomerization of 1,6-Enyne함영진; 최환근; 유하나, et al
2010-01-28광학활성 1,4-디데옥시-1,4-이미노-아라비니톨의 제조방법박동식; 심태보; 최환근, et al
2009-11-19단백질 키나아제 저해활성을 가지는 2,4,7-치환된 티에노[3,2-d]피리미딘 화합물김환; 박동식; 심태보, et al
2009-10-22단백질 키나아제 저해활성을 가지는 2,7-치환된 티에노[3,2-d]피리미딘 화합물김환; 심태보; 이정헌, et al
2009-08-20단백질 키나아제 저해활성을 갖는 1,3,6-치환된 인돌 화합물김환; 심태보; 오창현, et al
2010-01-29단백질 키나아제 저해활성을 갖는 비시클릭 헤테로아릴 유도체고명실; 김 환; 김맹섭, et al
2009-10-27단백질 키나아제 저해활성을 갖는 신규의 1,6-치환된 인돌 화합물김환; 심태보; 오창현, et al
2011-01-31단백질 키나아제 저해활성을 갖는 티에노[3,2-d]피리미딘 유도체김동욱; 김맹섭; 김은영, et al
2008-12-05비정상 세포 성장 질환의 치료를 위한 단백질 키나아제 저해제인 신규 인다졸 유도체, 이의 약학적으로 허용가능한염 및 이를 유효성분으로 함유하는 약학적 조성물권병목; 김환; 박동식, et al