Browsing byAuthorChoi, Hong Seok

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Showing results 1 to 16 of 16

Issue DateTitleAuthor(s)
2019-12All-trans Retinoic Acid Overcomes Acquired Resistance to PLX4032 via Inhibition of PIN1 in Melanoma CellsKim, Garam; Bhattarai, Poshan Yugal; Oh, Chang-Hyun; Choi, Hong Seok
2013-09Antiproliferative Diarylpyrazole Derivatives as Dual Inhibitors of the ERK Pathway and COX-2El-Gamal, Mohammed I.; Choi, Hong Seok; Yoo, Kyung Ho; Baek, Daejin; Oh, Chang-Hyun
2016-12Design and synthesis of a new series of highly potent RAF kinase-inhibiting triarylpyrazole derivatives possessing antiproliferative activity against melanoma cellsKhan, Mohammad Ashrafuddin; El-Gamal, Mohammed I.; Tarazi, Hamadeh; Choi, Hong Seok; Oh, Chang-Hyun
2019-03-31Design and synthesis of a novel series of highly potent RAF kinase-inhibiting triarylpyrazole derivatives with potential antiproliferative activity against melanomaEl-Gamal, Mohammed; Khan, Mohammad Ashrafuddin; Oh, Chang-Hyun; Choi, Hong Seok; Tarazi, Hamadeh
2011-11Design, Synthesis, and Antiproliferative Activity of 3,4-Diarylpyrazole-1-carboxamide Derivatives Against Melanoma Cell LineEl-Gamal, Mohammed I.; Choi, Hong Seok; Cho, Hae-Guk; Hong, Jun Hee; Yoo, Kyung Ho; Oh, Chang-Hyun
2012-09-20Design, Synthesis, and Preliminary Cytotoxicity Evaluation of New Diarylureas and Diarylamides Possessing 1,3,4-Triarylpyrazole ScaffoldChoi, Won-Kyoung; El-Gamal, Mohammed I.; Choi, Hong Seok; Hong, Jun Hee; Baek, Daejin; Choi, Kihang; Oh, Chang-Hyun
2015-05-05Design, synthesis, in vitro antiproliferative evaluation, and kinase inhibitory effects of a new series of imidazo[2,1-b]thiazole derivativesAbdel-Maksoud, Mohammed S.; Kim, Mi-Ryeong; El-Gamal, Mohammed I.; El-Din, Mahmoud M. Gamal; Tae, Jinsung; Choi, Hong Seok; Lee, Kyung-Tae; Yoo, Kyung Ho; Oh, Chang-Hyun
2021-05Discovery of New Imidazo[2,1-b]thiazole Derivatives as Potent Pan-RAF Inhibitors with Promising In Vitro and In Vivo Anti-melanoma ActivityAbdel-Maksoud, Mohammed S.; El-Gamal, Mohammed, I; Lee, Bong S.; El-Din, Mahmoud M. Gamal; Jeon, Hong R.; Kwon, Dow; Ammar, Usama M.; Mersal, Karim, I; Ali, Eslam M. H.; Lee, Kyung-Tae; Yoo, Kyung Ho; Han, Dong Keun; Lee, Jae Kyun; Kim, Garam; Choi, Hong Seok; Kwon, Young Jik; Lee, Kwan Hyi; Oh, Chang Hyun
2013-09Inhibitory Effects of a New 1H-Pyrrolo[3,2-c]pyridine Derivative, KIST101029, on Activator Protein-1 Activity and Neoplastic Cell Transformation Induced by Insulin-Like Growth Factor-1Yun, Hyo Jeong; Kim, Garam; Khanal, Prem; Kim, Karam; Oh, Chang-Hyun; Choi, Hoo-Kyun; Sohn, Honglae; Choi, Hong Seok
2020-10-15Modification of imidazothiazole derivatives gives promising activity in B-Raf kinase enzyme inhibition; synthesis, in vitro studies and molecular dockingAmmar, Usama M.; Abdel-Maksoud, Mohammed S.; Mersal, Karim, I; Ali, Eslam M. H.; Yoo, Kyung Ho; Choi, Hong Seok; Lee, Jae Kyun; Cha, Sun Young; Oh, Chang-Hyun
2013-12New diarylamides and diarylureas possessing 8-amino(acetamido) quinoline scaffold: Synthesis, antiproliferative activities against melanoma cell lines, kinase inhibition, and in silico studiesKoh, Eun Jeong; El-Gamal, Mohammed I.; Oh, Chang-Hyun; Lee, So Ha; Sim, Taebo; Kim, Garam; Choi, Hong Seok; Hong, Jun Hee; Lee, Sang-gi; Yoo, Kyung Ho
2011-12New diarylureas and diarylamides containing 1,3,4-triarylpyrazole scaffold: Synthesis, antiproliferative evaluation against melanoma cell lines, ERK kinase inhibition, and molecular docking studiesChoi, Won-Kyoung; El-Gamal, Mohammed I.; Choi, Hong Seok; Baek, Daejin; Oh, Chang-Hyun
2020-09Novel Imidazo[2,1-b]oxazole Derivatives Inhibit Epithelial Cell Transformation and Triple Negative Breast Cancer TumorigenesisBhattarai, Poshan Yugal; Oh, Chang-Hyun; Kim, Garam; Kim, Min Soo; Lee, Bong Sang; Choi, Hong Seok
2013-07Novel Quinolinylaminoisoquinoline Bioisosteres of Sorafenib as Selective RAFI Kinase Inhibitors: Design, Synthesis, and Antiproliferative Activity against Melanoma Cell LineCho, Hye Jung; El-Gamal, Mohammed Ibrahim; Oh, Chang-Hyun; Lee, So Ha; Sim, Taebo; Kim, Garam; Choi, Hong Seok; Choi, Jung Hoon; Yoo, Kyung Ho
2022-06Potent Imidazothiazole-based Inhibitor of BRAF V600E Overcomes Acquired Resistance via Inhibition of RAF Dimerization in PLX4032-resistant MelanomaPoudel, Muna; Kim, Garam; Bhattarai, Poshan Yugal; Shin, Seung; Zaraei, Seyed-Omar; Oh, Chang-Hyun; Choi, Hong Seok
2012-11-20Synthesis and Antiproliferative Activity of New Aminoisoquinolinylurea Derivatives against Melanoma Cell LineCho, Hye Jung; El-Gamal, Mohammed I.; Oh, Chang-Hyun; Lee, So Ha; Kim, Garam; Hong, Jun Hee; Choi, Hong Seok; Yoo, Kyung Ho

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