Browsing byAuthorHassan, Ahmed H. E.
Showing results 1 to 25 of 25
| Issue Date | Title | Author(s) |
|---|---|---|
| 2021-11 | AKF-D52, a Synthetic Phenoxypyrimidine-Urea Derivative, Triggers Extrinsic/Intrinsic Apoptosis and Cytoprotective Autophagy in Human Non-Small Cell Lung Cancer Cells | Gil, Hyo-Sun; Lee, Jeong-Hun; Farag, Ahmed K.; Hassan, Ahmed H. E.; Chung, Kyung-Sook; Choi, Jung-Hye; Roh, Eun-Joo; Lee, Kyung-Tae |
| 2017-10 | Concise Synthesis of Aloesone and Aloesol Natural Products | Kim, Hyoung Ja; Parveen, Shehlar; Lee, Jiyong; Hassan, Ahmed H. E.; Jin, Changbae; Saleem, Muhammad; Lee, Yong Sup |
| 2018-02 | Construction of 8-Azabicyclo[3.2.1]octanes via Sequential DDQ-Mediated Oxidative Mannich Reactions of N-Aryl Pyrrolidines | Jo, Hanbyeol; Hassan, Ahmed H. E.; Jung, Seung Young; Lee, Jae Kyun; Cho, Yong Seo; Min, Sun-Joon |
| 2018-09-05 | Design, synthesis and biological evaluation of novel thiazolidinedione derivatives as irreversible allosteric IKK-beta modulators | Elkamhawy, Ahmed; Kim, Nam Youn; Hassan, Ahmed H. E.; Park, Jung-eun; Yang, Jeong-Eun; Oh, Kwang-Seok; Lee, Byung Ho; Lee, Mi Young; Shin, Kye Jung; Lee, Kyung-Tae; Hur, Wooyoung; Roh, Eun Joo |
| 2017-06-15 | Design, synthesis, biological evaluation and molecular modelling of 2-(2-aryloxyphenyl)-1,4-dihydroisoquinolin-3(2H)-ones: A novel class of TSPO ligands modulating amyloid-beta-induced mPTP opening | Elkamhawy, Ahmed; Park, Jung-eun; Hassan, Ahmed H. E.; Pae, Ae Nim; Lee, Jiyoun; Park, Beoung-Geon; Paik, Sora; Do, Jimin; Park, Jong-Hyun; Park, Ki Duk; Moon, Bongjin; Park, Woo Kyu; Cho, Heeyeong; Jeong, Dae Young; Roh, Eun Joo |
| 2020-10 | Diarylurea derivatives comprising 2,4-diarylpyrimidines: Discovery of novel potential anticancer agents via combined failed-ligands repurposing and molecular hybridization approaches | Farag, Ahmed Karam; Hassan, Ahmed H. E.; Chung, Kyung-Sook; Lee, Jeong-Hun; Gil, Hyo-Sun; Lee, Kyung-Tae; Roh, Eun Joo |
| 2017-03-10 | Discovery of 1-(3-(benzyloxy)pyridin-2-yl)-3-(2-(piperazin-1-yl)ethyl)urea: A new modulator for amyloid beta-induced mitochondrial dysfunction | Elkamhawy, Ahmed; Park, Jung-Eun; Hassan, Ahmed H. E.; Ra, Hyunhwa; Pae, Ae Nim; Lee, Jiyoun; Park, Beoung-Geon; Moon, Bongjin; Park, Hyun-Mee; Roh, Eun Joo |
| 2019-05 | EGFR inhibitors from cancer to inflammation: Discovery of 4-fluoro-N-(4-(3-(trifluoromethyl)phenoxy)pyrimidin-5-yl)benzamide as a novel anti-inflammatory EGFR inhibitor | Elkamhawy, Ahmed; Hassan, Ahmed H. E.; Paik, Sora; Lee, Yong Sup; Lee, Hwi-Ho; Shin, Ji-Sun; Lee, Kyung-Tae; Roh, Eun Joo |
| 2019-01-15 | First-in-class DAPK1/CSF1R dual inhibitors: Discovery of 3,5-dimethoxy-N-(4-(4-methoxyphenoxy)-24(6-morpholinopyridin-3-yl)amino) pyrimidin-5-yl)benzamide as a potential anti-tauopathies agent | Farag, Ahmed Karam; Hassan, Ahmed H. E.; Jeong, Hyeanjeong; Kwon, Youngji; Choi, Jin Gyu; Oh, Myung Sook; Park, Ki Duk; Kim, Yun Kyung; Roh, Eun Joo |
| 2020-06 | Fluorinated CRA13 analogues: Synthesis, in vitro evaluation, radiosynthesis, in silico and in vivo PET study | Hassan, Ahmed H. E.; Park, Kyung Tae; Kim, Hye Jin; Lee, Hyo Jong; Kwon, Yeong Ho; Hwang, Ji Young; Jang, Choon-Gon; Chung, Jin Hwa; Park, Ki Duk; Lee, Sang Joo; Oh, Seung Jun; Lee, Yong Sup |
| 2017-11 | Hit discovery of 4-amino-N-(4-(3-(trifluoromethyl)phenoxy)pyrimidin-5-yl)benzamide: A novel EGFR inhibitor from a designed small library | Elkamhawy, Ahmed; Paik, Sora; Hassan, Ahmed H. E.; Lee, Yong Sup; Roh, Eun Joo |
| 2022-09 | Identification of Novel Aryl Carboxamide Derivatives as Death-Associated Protein Kinase 1 (DAPK1) Inhibitors with Anti-Proliferative Activities: Design, Synthesis, In Vitro, and In Silico Biological Studies | Elkamhawy, Ahmed; Paik, Sora; Ali, Eslam M. H.; Hassan, Ahmed H. E.; Kang, So Jin; Lee, Kyeong; Roh, Eun Joo |
| 2024-01 | Integrating computational methods guided the discovery of phytochemicals as potential Pin1 inhibitors for cancer: pharmacophore modeling, molecular docking, MM-GBSA calculations and molecular dynamics studies | Alzain, Abdulrahim A.; Elbadwi, Fatima A.; Shoaib, Tagyedeen H.; Sherif, Asmaa E.; Osman, Wadah; Ashour, Ahmed; Mohamed, Gamal A.; Ibrahim, Sabrin R. M.; Roh, Eun Joo; Hassan, Ahmed H. E. |
| 2019-11 | Optimization study towards more potent thiazolidine-2,4-dione IKK-beta modulator: Synthesis, biological evaluation and in silico docking simulation | Elkamhawy, Ahmed; Kim, Nam Youn; Hassan, Ahmed H. E.; Park, Jung-eun; Yang, Jeong-Eun; Elsherbeny, Mohamed H.; Paik, Sora; Oh, Kwang-Seok; Lee, Byung Ho; Lee, Mi Young; Shin, Kye Jung; Pae, Ae Nim; Lee, Kyung-Tae; Roh, Eun Joo |
| 2022-12 | Positional scanning of natural product hispidol's ring-B: discovery of highly selective human monoamine oxidase-B inhibitor analogues downregulating neuroinflammation for management of neurodegenerative diseases | Hassan, Ahmed H. E.; Kim, Hyeon Jeong; Gee, Min Sung; Park, Jong-Hyun; Jeon, Hye Rim; Lee, Cheol Jung; Choi, Yeonwoo; Moon, Suyeon; Lee, Danbi; Lee, Jong Kil; Park, Ki Duk; Lee, Yong Sup |
| 2018-09-05 | Pyrazinyl ureas revisited: 1-(3-(Benzyloxy)pyrazin-2-yl)-3-(3,4-dichlorophenyl)urea, a new blocker of A beta-induced mPTP opening for Alzheimer's disease | Elkamhawy, Ahmed; Park, Jung-eun; Hassan, Ahmed H. E.; Pae, Ae Nim; Lee, Jiyoun; Paik, Sora; Park, Beoung-Geon; Roh, Eun Joo |
| 2018-05-10 | Repositioning of the antipsychotic trifluoperazine: Synthesis, biological evaluation and in silico study of trifluoperazine analogs as anti-glioblastoma agents | Kang, Seokmin; Lee, Jung Moo; Jeon, Borami; Elkamhawy, Ahmed; Paik, Sora; Hong, Jinpyo; Oh, Soo-Jin; Paek, Sun Ha; Lee, C. Justin; Hassan, Ahmed H. E.; Kang, Sang Soo; Roh, Eun Joo |
| 2020-01-01 | Reprofiling of pyrimidine-based DAPK1/CSF1R dual inhibitors: identification of 2,5-diamino-4-pyrimidinol derivatives as novel potential anticancer lead compounds | Farag, Ahmed K.; Hassan, Ahmed H. E.; Ahn, Byung Sun; Park, Ki Duk; Roh, Eun Joo |
| 2023-05 | Synthesis and Biological Evaluation of O-6-Aminoalkyl-Hispidol Analogs as Multifunctional Monoamine Oxidase-B Inhibitors towards Management of Neurodegenerative Diseases | Hassan, Ahmed H. E.; Kim, Hyeon Jeong; Park, Keontae; Choi, Yeonwoo; Moon, Suyeon; Lee, Chae Hyeon; Kim, Yeon Ju; Cho, Soo Bin; Gee, Min Sung; Lee, Danbi; Park, Jong-Hyun; Lee, Jong Kil; Ryu, Jong Hoon; Park, Ki Duk; Lee, Yong Sup |
| 2016-01-01 | Synthesis and biological evaluation of picolinamides and thiazole-2-carboxamides as mGluR5 (metabotropic glutamate receptor 5) antagonists | Hoang Nam Vu; Kim, Ji Young; Hassan, Ahmed H. E.; Choi, Kihang; Park, Jong-Hyun; Park, Ki Duk; Lee, Jae Kyun; Pae, Ae Nim; Choo, Hyunah; Min, Sun-Joon; Cho, Yong Seo |
| 2018-01-20 | Synthesis and evaluation of 2-(3-arylureido)pyridines and 2-(3-arylureido)pyrazines as potential modulators of A beta-induced mitochondrial dysfunction in Alzheimer's disease | Elkamhawy, Ahmed; Park, Jung-eun; Hassan, Ahmed H. E.; Pae, Ae Nim; Lee, Jiyoun; Park, Beoung-Geon; Roh, Eun Joo |
| 2017-12-01 | Synthesis and evaluation of new pyridyl/pyrazinyl thiourea derivatives: Neuroprotection against amyloid-beta-induced toxicity | Park, Jung-eun; Elkamhawy, Ahmed; Hassan, Ahmed H. E.; Pae, Ae Nim; Lee, Jiyoun; Paik, Sora; Park, Beoung-Geon; Roh, Eun Joo |
| 2018-10-01 | Synthesis of oxidative metabolites of CRA13 and their analogs: Identification of CRA13 active metabolites and analogs thereof with selective CB2R affinity | Hassan, Ahmed H. E.; Cho, Min Chang; Kim, Hye In; Yang, Ji Seul; Park, Kyung Tae; Hwang, Ji Young; Jang, Choon-Gon; Park, Ki Duk; Lee, Yong Sup |
| 2015-06-05 | Synthesis of the Tricyclic Ring Structure of Daphnanes via Intramolecular [4+3] Cycloaddition/SmI2-Pinacol Coupling | Hassan, Ahmed H. E.; Lee, Jae Kyun; Pae, Ae Nim; Min, Sun-Joon; Cho, Yong Seo |
| 2020-02-15 | Thiazolidine-2,4-dione-based irreversible allosteric IKK-beta kinase inhibitors: Optimization into in vivo active anti-inflammatory agents | Elkamhawy, Ahmed; Kim, Nam Youn; Hassan, Ahmed H. E.; Park, Jung-eun; Paik, Sora; Yang, Jeong-Eun; Oh, Kwang-Seok; Lee, Byung Ho; Lee, Mi Young; Shin, Kye Jung; Pae, Ae Nim; Lee, Kyung-Tae; Roh, Eun Joo |
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