Browsing byAuthorPark, Jong-Hyun
Showing results 1 to 30 of 35
| Issue Date | Title | Author(s) |
|---|---|---|
| 2020-01-01 | A novel chalcone derivative as Nrf2 activator attenuates learning and memory impairment in a scopolamine-induced mouse model | Kim, Hyeon Jeong; Jang, Bo Ko; Park, Jong-Hyun; Choi, Ji Won; Park, Sun Jun; Byeon, Seong Rim; Pae, Ae Nim; Lee, Yang Sup; Cheong, Eunji; Park, Ki Duk |
| 2015-09 | Antioxidant and Anti-Inflammatory Activities of a Natural Compound, Shizukahenriol, through Nrf2 Activation | Park, Jong-Hyun; Choi, Ji Won; Ju, Eun Ji; Pae, Ae Nim; Park, Ki Duk |
| 2019-07 | Antioxidant, Anti-inflammatory, and Neuroprotective Effects of Novel Vinyl Sulfonate Compounds as Nrf2 Activator | Choi, Ji Won; Shin, Su Jeong; Kim, Hyeon Ji; Park, Jong-Hyun; Kim, Hyeon Jeong; Lee, Elijah Hwejin; Pae, Ae Nim; Bahn, Yong Sun; Park, Ki Duk |
| 2017-06-15 | Design, synthesis, biological evaluation and molecular modelling of 2-(2-aryloxyphenyl)-1,4-dihydroisoquinolin-3(2H)-ones: A novel class of TSPO ligands modulating amyloid-beta-induced mPTP opening | Elkamhawy, Ahmed; Park, Jung-eun; Hassan, Ahmed H. E.; Pae, Ae Nim; Lee, Jiyoun; Park, Beoung-Geon; Paik, Sora; Do, Jimin; Park, Jong-Hyun; Park, Ki Duk; Moon, Bongjin; Park, Woo Kyu; Cho, Heeyeong; Jeong, Dae Young; Roh, Eun Joo |
| 2021-02-15 | Development and optimization of halogenated vinyl sulfones as Nrf2 activators for the treatment of Parkinson's disease | Choi, Ji Won; Kim, Siwon; Yoo, Jong Seok; Kim, Hyeon Jeong; Kim, Hyeon Ji; Kim, Byung Eun; Lee, Elijah Hwejin; Lee, Yong Sup; Park, Jong-Hyun; Park, Ki Duk |
| 2022-04 | Development of Dibenzothiazepine Derivatives as Multifunctional Compounds for Neuropathic Pain | Jung, Young-Hwan; Kim, Yeo Ok; Kang, Koon Mook; Lee, Hyung Gon; Son, Borum; Han, Xuehao; Oh, Eunseok; Kim, Siwon; Seo, Seon Hee; Park, Jong-Hyun; Park, Ki Duk; Kim, Woong Mo; Yoon, Myung Ha; Kim, Yong-Chul |
| 2021-11 | Discovery of 3,4-dichloro-N-(1H-indol-5-yl)benzamide: A highly potent, selective, and competitive hMAO-B inhibitor with high BBB permeability and action | Elkamhawy, Ahmed; Kim, Hyeon Jeong; Elsherbeny, Mohamed H.; Paik, Sora; Park, Jong-Hyun; Gotina, Lizaveta; Abdellattif, Magda H.; Gouda, Noha A.; Cho, Jungsook; Lee, Kyeong; Pae, Ae Nim; Park, Ki Duk; Roh, Eun Joo |
| 2017-01-05 | Discovery of benzimidazole derivatives as modulators of mitochondrial function: A potential treatment for Alzheimer's disease | Kim, TaeHun; Yang, Ha Yun; Park, Beoung Gun; Jung, Seo Yun; Park, Jong-Hyun; Park, Ki Duk; Min, Sun-Joon; Tae, Jinsung; Yang, Hyejin; Cho, Suengmok; Cho, Sung Jin; Song, Hyundong; Mook-Jung, Inhee; Lee, Jiyoun; Pae, Ae Nim |
| 2020-01 | Discovery of N-(1-(3-fluorobenzoyl)-1H-indol-5-yl)pyrazine-2-carboxamide: a novel, selective, and competitive indole-based lead inhibitor for human monoamine oxidase B | Elkamhawy, Ahmed; Paik, Sora; Kim, Hyeon Jeong; Park, Jong-Hyun; Londhe, Ashwini M.; Lee, Kyeong; Pae, Ae Nim; Park, Ki Duk; Roh, Eun Joo |
| 2019-10-17 | Discovery of Novel Biased Opioid Receptor Ligands through Structure-Based Pharmacophore Virtual Screening and Experiment | Jeong, Pyeonghwa; Kim, Soo-Kyung; Li, Quanjie; Oh, Su-jin; Son, Seonil; Chen, Guangju; Tan, Hongwei; Kim, Siwon; Park, Jong-Hyun; Park, Ki Duk; Kim, Yeo Ok; Yoon, Myung Ha; Kim, Yong-Chul; Goddard, William A., III |
| 2017-12-01 | Discovery of thienopyrrolotriazine derivatives to protect mitochondrial function against A beta-induced neurotoxicity | Kim, TaeHun; Son, Woo Seung; Morshed, Mohammad Neaz; Londhe, Ashwini M.; Jung, Seo Yun; Park, Jong-Hyun; Park, Woo-Kyu; Lim, Sang Min; Park, Ki Duk; Cho, Sung Jin; Jeong, Kyu-Sung; Lee, Jiyoun; Pae, Ae Nim |
| 2023-08 | Exploration of Tetrahydroisoquinoline- and Benzo[c]azepine-Based Sphingosine 1-Phosphate Receptor 1 Agonists for the Treatment of Multiple Sclerosis | Cha, Eunji; Kim, Jushin; Gotina, Lizaveta; Kim, Jaehwan; Kim, Hyeon Jeong; Seo, Seon Hee; Park, Jeong-Eun; Joo, Jeongmin; Kang, Minsik; Lee, Jaeick; Hwang, Hayoung; Kim, Hak Joong; Pae, Ae Nim; Park, Ki Duk; Park, Jong-Hyun; Lim, Sang Min |
| 2020-12 | Identification and evaluation of a napyradiomycin as a potent Nrf2 activator: Anti-oxidative and anti-inflammatory activities | Choi, Ji Won; Kim, Geum Jin; Kim, Hyeon Jeong; Nam, Joo-Won; Kim, Jushin; Chin, Jungwook; Park, Jong-Hyun; Choi, Hyukjae; Park, Ki Duk |
| 2017-07 | Indole-Substituted Benzothiazoles and Benzoxazoles as Selective and Reversible MAO-B Inhibitors for Treatment of Parkinson's Disease | Nam, Min-Ho; Park, Moosung; Park, Hyeri; Kim, Youngjae; Yoon, Seulki; Sawant, Vikram Shahaji; Choi, Ji Won; Park, Jong-Hyun; Park, Ki Duk; Min, Sun-Joon; Lee, C. Justin; Chooaii, Hyunah |
| 2021-07 | KDS2010, a Newly Developed Reversible MAO-B Inhibitor, as an Effective Therapeutic Candidate for Parkinson's Disease | Nam, Min-Ho; Park, Jong-Hyun; Song, Hyo jung; Choi, Ji Won; Kim, Siwon; 장보고; Yoon, Hyung Ho; Heo, Jun Young; Lee, Hyowon; An, Heeyoung; Kim, Hyeon Jeong; Park, Sun Jun; Cho, Doo-Wan; Yang, Young-Su; Han, Su-Cheol; Kim, Sangwook; Oh, Soo-Jin; Jeon, Sang Ryong; Park, Ki Duk; Lee, C. Justin |
| 2019-09 | Mammalian target of rapamycin complex 1 and its downstream effector collapsin response mediator protein-2 drive reinstatement of alcohol reward seeking | Ben Hamida, Sami; Laguesse, Sophie; Morisot, Nadege; Park, Jong-Hyun; Phuamluong, Khanhky; Berger, Anthony L.; Park, Ki Duk; Ron, Dorit |
| 2017-10 | Membrane-bound Dickkopf-1 in Foxp3(+) regulatory T cells suppresses T-cell-mediated autoimmune colitis | Chae, Wook-Jin; Park, Jong-Hyun; Henegariu, Octavian; Yilmaz, Saliha; Hao, Liming; Bothwell, Alfred L. M. |
| 2019-03 | Newly developed reversible MAO-B inhibitor circumvents the shortcomings of irreversible inhibitors in Alzheimer's disease | Park, Jong-Hyun; Ju, Yeon Ha; Choi, Ji Won; Song, Hyo Jung; Jang, Bo Ko; Woo, Junsung; Chun, Heejung; Kim, Hyeon Jeong; Shin, Su Jeong; Yarishkin, Oleg; Jo, Seonmi; Park, Mijeong; Yeon, Seul Ki; Kim, Siwon; Kim, Jeongyeon; Nam, Min-Ho; Londhe, Ashwini M.; Kim, Jina; Cho, Sung Jin; Cho, Suengmok; Lee, Changho; Hwang, Sung Yeoun; Kim, Sang Wook; Oh, Soo-Jin; Cho, Jeiwon; Pae, Ae Nim; Lee, C. Justin; Park, Ki Duk |
| 2020-05 | Nrf2 activator via interference of Nrf2-Keap1 interaction has antioxidant and anti-inflammatory properties in Parkinson's disease animal model | Kim, Siwon; Viswanath, Ambily Nath Indu; Park, Jong-Hyun; Lee, Ha Eun; Park, A. Yeong; Choi, Ji Won; Kim, Hyeon Jeong; Londhe, Ashwini M.; Jang, Bo Ko; Lee, Jaeick; Hwang, Hayoung; Lim, Sang Min; Pae, Ae Nim; Park, Ki Duk |
| 2021-11-11 | Optimization and Evaluation of Novel Antifungal Agents for the Treatment of Fungal Infection | Choi, Ji Won; Lee, Kyung-Tae; Kim, Siwon; Lee, Ye Rim; Kim, Hyeon Ji; Seo, Kyung Jin; Lee, Myung Ha; Yeon, Seul Ki; Jang, Bo Ko; Park, Sun Jun; Kim, Hyeon Jeong; Park, Jong-Hyun; Kim, Dahee; Lee, Dong-Gi; Cheong, Eunji; Lee, Jong-Seung; Bahn, Yong-Sun; Park, Ki Duk |
| 2023-08 | Optimization and evaluation of pyridinyl vinyl sulfones as Nrf2 activator for the antioxidant and anti-inflammatory effects | Kim, Byungeun; Kim, Rium; Kim, Hyeon Jeong; Kim, Yoowon; Park, Sun Jun; Lee, Elijah Hwejin; Kim, Jushin; Kim, Jaehwan; Choi, Ji Won; Park, Jong-Hyun; Park, Ki Duk |
| 2019-01 | Optimization of Vinyl Sulfone Derivatives as Potent Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Activators for Parkinson's Disease Therapy | Choi, Ji Won; Kim, Siwon; Park, Jong-Hyun; Kim, Hyeon Jeong; Shin, Su Jeon; Kim, Jin Woo; Woo, Seo Yeon; Lee, Changho; Han, Sang Moon; Lee, Jaeick; Pae, Ae Nim; Han, Gyoonhee; Park, Ki Duk |
| 2022-12 | Positional scanning of natural product hispidol's ring-B: discovery of highly selective human monoamine oxidase-B inhibitor analogues downregulating neuroinflammation for management of neurodegenerative diseases | Hassan, Ahmed H. E.; Kim, Hyeon Jeong; Gee, Min Sung; Park, Jong-Hyun; Jeon, Hye Rim; Lee, Cheol Jung; Choi, Yeonwoo; Moon, Suyeon; Lee, Danbi; Lee, Jong Kil; Park, Ki Duk; Lee, Yong Sup |
| 2020-06-17 | PyrPeg, a Blood-Brain-Barrier-Penetrating Two-Photon Imaging Probe, Selectively Detects Neuritic Plaques, Not Tau Aggregates | Choi, Ji-Woo; Ju, Yeon Ha; Choi, Yunsook; Hyeon, Seung Jae; Gadhe, Changdev G.; Park, Jong-Hyun; Kim, Mun Seok; Baek, Seungyeop; Kim, YoungSoo; Park, Ki Duk; Pae, Ae Nim; Ryu, Hoon; Lee, C. Justin; Cho, Bong Rae |
| 2016-02-17 | Screening, Synthesis, and In Vitro Evaluation of Vinyl Sulfones as Inhibitors of Complement-Dependent Cytotoxicity in Neuromyelitis Optica | Ju, Eun Ji; Yeon, Seul Ki; Park, Jong-Hyun; Cheon, So Young; Choi, Ji Won; Ha, Taehwan; Jang, Bo Ko; Kim, Siwon; Kang, Yong Gu; Hwang, Hayoung; Cho, Sung Jin; Cheong, Eunji; Bahn, Yong Sun; Pae, Ae Nim; Kim, Sung Min; Park, Ki Duk |
| 2020-12 | Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer's disease via H2O2- production | Chun, Heejung; Im, Hyeonjoo; Kang, You Jung; Kim, Yunha; Shin, Jin Hee; Won, Woojin; Lim, Jiwoon; Ju, Yeonha; Park, Yongmin Mason; Kim, Sunpil; Lee, Seung Eun; Lee, Jaekwang; Woo, Junsung; Hwang, Yujin; Cho, Hyesun; Jo, Seonmi; Park, Jong-Hyun; Kim, Daesoo; Kim, Doo Yeon; Seo, Jeong-Sun; Gwag, Byoung Joo; Kim, Young Soo; Park, Ki Duk; Kaang, Bong-Kiun; Cho, Hansang; Ryu, Hoon; Lee, C. Justin |
| 2015-04 | Simultaneous Enhancement of Upconversion and Downshifting Luminescence via Plasmonic Structure | Lee, Kyu-Tae; Park, Jong-Hyun; Kwon, S. Joon; Kwon, Hyun-Keun; Kyhm, Jihoon; Kwak, Kyung-Won; Jang, Ho Seong; Kim, Su Yeon; Han, Joon Soo; Lee, Sung-Hwan; Shin, Dong-Hun; Ko, Hyungduk; Han, Il-Ki; Ju, Byeong-Kwon; Kwon, Soong-Hong; Ko, Doo-Hyun |
| 2023-05 | Synthesis and Biological Evaluation of O-6-Aminoalkyl-Hispidol Analogs as Multifunctional Monoamine Oxidase-B Inhibitors towards Management of Neurodegenerative Diseases | Hassan, Ahmed H. E.; Kim, Hyeon Jeong; Park, Keontae; Choi, Yeonwoo; Moon, Suyeon; Lee, Chae Hyeon; Kim, Yeon Ju; Cho, Soo Bin; Gee, Min Sung; Lee, Danbi; Park, Jong-Hyun; Lee, Jong Kil; Ryu, Jong Hoon; Park, Ki Duk; Lee, Yong Sup |
| 2016-01-01 | Synthesis and biological evaluation of picolinamides and thiazole-2-carboxamides as mGluR5 (metabotropic glutamate receptor 5) antagonists | Hoang Nam Vu; Kim, Ji Young; Hassan, Ahmed H. E.; Choi, Kihang; Park, Jong-Hyun; Park, Ki Duk; Lee, Jae Kyun; Pae, Ae Nim; Choo, Hyunah; Min, Sun-Joon; Cho, Yong Seo |
| 2018-11-01 | Synthesis and Development of Novel Compounds Selectively Targeting on Sphingosine 1-Phosphate Receptor 1 (S1P1) for Treatment of Multiple Sclerosis | Yeon, Seul Ki; Park, Jong-Hyun; Park, Ki Duk; Kim, Hyeon Jeong; Shin, Su Jeong |
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