Full metadata record

DC Field Value Language
dc.contributor.authorLim, Taehwan-
dc.contributor.authorLee, Kiuk-
dc.contributor.authorKim, Ryun Hee-
dc.contributor.authorRyu, Juhee-
dc.contributor.authorCha, Kwang Hyun-
dc.contributor.authorPark, Sun Young-
dc.contributor.authorKoo, Song Yi-
dc.contributor.authorHwang, Keum Taek-
dc.date.accessioned2024-01-19T10:02:09Z-
dc.date.available2024-01-19T10:02:09Z-
dc.date.created2023-03-16-
dc.date.issued2023-03-
dc.identifier.issn1226-7708-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/113949-
dc.description.abstractIn our previous study, black raspberry (BR) reduced the serum levels of trimethylamine-N-oxide and cholesterol in rats fed excessive choline with a high-fat diet (HFC). We hypothesized that gut microbiota could play a crucial role in the production of trimethylamine and microbial metabolites, and BR could influence gut microbial composition. This study aimed to elucidate the role of BR on changes in gut microbiota and microbial metabolites in the rats. The phylogenetic diversity of gut microbiota was reduced in the rats fed HFC, while that in the BR-fed group was restored. The BR supplementation enriched Bifidobacterium and reduced Clostridium cluster XIVa. In the BR-fed group, most cecal bile acids and hippuric acid increased, while serum lithocholic acid was reduced. The BR supplementation upregulated Cyp7a1 and downregulated Srebf2. These results suggest that BR extract may change gut bacterial community, modulate bile acids, and regulate gene expression toward reducing cholesterol.-
dc.languageEnglish-
dc.publisher한국식품과학회-
dc.titleEffects of black raspberry extract on gut microbiota, microbial metabolites, and expressions of the genes involved in cholesterol and bile acid metabolisms in rats fed excessive choline with a high-fat diet-
dc.typeArticle-
dc.identifier.doi10.1007/s10068-023-01267-4-
dc.description.journalClass1-
dc.identifier.bibliographicCitationFood Science and Biotechnology, v.32, no.4, pp.577 - 578-
dc.citation.titleFood Science and Biotechnology-
dc.citation.volume32-
dc.citation.number4-
dc.citation.startPage577-
dc.citation.endPage578-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.description.journalRegisteredClasskci-
dc.identifier.kciidART002939026-
dc.identifier.wosid000929983900003-
dc.identifier.scopusid2-s2.0-85147980056-
dc.relation.journalWebOfScienceCategoryFood Science & Technology-
dc.relation.journalResearchAreaFood Science & Technology-
dc.type.docTypeArticle; Early Access-
dc.subject.keywordPlusANTHOCYANINS-
dc.subject.keywordPlusRUBUS-
dc.subject.keywordPlusINTERVENTION-
dc.subject.keywordPlusIMPACT-
dc.subject.keywordAuthorRubus occidentalis-
dc.subject.keywordAuthorCholine-
dc.subject.keywordAuthorTMAO-
dc.subject.keywordAuthorGut microbiome-
dc.subject.keywordAuthorBile acid-
Appears in Collections:
KIST Article > 2023
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE