A new route to quinolone and indole skeletones via ketone- and ester-imide cyclodehydration reactions
- A new route to quinolone and indole skeletones via ketone- and ester-imide cyclodehydration reactions
- 김근철; 금교창
- Issue Date
- VOL 45, NO 10, 1979-1988
- Ketone-imide cyclodehydration reactions of aromatic succinimide and phthalimide (7, 8) have aforded quinolone acids (11, 12). Further transformation of the acids provided the corresponding esters (13, 14) and vinylogous urethanes (9, 10). Similarly, ester-imide cyclodehydration reactions of aromatic imide esters (19, 20) have afforded indole acids (23, 24).
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