Full metadata record

DC Field Value Language
dc.contributor.authorLee, Jooyoung-
dc.contributor.authorSong, Boa-
dc.contributor.authorSubbiah, Ramesh-
dc.contributor.authorChung, Justin J.-
dc.contributor.authorChoi, U. Hyeok-
dc.contributor.authorPark, Kwideok-
dc.contributor.authorKim, Sang-Heon-
dc.contributor.authorOh, Seung Ja-
dc.date.accessioned2024-01-19T20:34:11Z-
dc.date.available2024-01-19T20:34:11Z-
dc.date.created2021-09-02-
dc.date.issued2019-02-21-
dc.identifier.issn2045-2322-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/120333-
dc.description.abstractHydrogels have been developed and applied to various biomedical applications due to their biocompatibility. However, understanding of modulation between cells to hydrogel interface is still unclear, and parameters to explain the interaction are not sophisticated enough. In this report, we studied the effect of polymer chain flexibility on cell adhesion to various hydrogel constructs of collagen and fibrin gels. Specifically, novel method of semi-flexible model-based analysis confirmed that chain flexibility mediated microstructure of the hydrogels is a critical factor for cell adhesion on their surfaces. The proposed analysis showed possibility of more accurate prediction of biocompatibility of hydrogels, and it should be considered as one of the important criteria for polymer design and selections for enhancing both biocompatibility and biofunctionality.-
dc.languageEnglish-
dc.publisherNATURE PUBLISHING GROUP-
dc.subjectCOLLAGEN-
dc.subjectSTIFFNESS-
dc.subjectNETWORKS-
dc.subjectMODULUS-
dc.titleEffect of chain flexibility on cell adhesion: Semi-flexible model-based analysis of cell adhesion to hydrogels-
dc.typeArticle-
dc.identifier.doi10.1038/s41598-019-38951-7-
dc.description.journalClass1-
dc.identifier.bibliographicCitationSCIENTIFIC REPORTS, v.9-
dc.citation.titleSCIENTIFIC REPORTS-
dc.citation.volume9-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000459281500032-
dc.identifier.scopusid2-s2.0-85061916469-
dc.relation.journalWebOfScienceCategoryMultidisciplinary Sciences-
dc.relation.journalResearchAreaScience & Technology - Other Topics-
dc.type.docTypeArticle-
dc.subject.keywordPlusCOLLAGEN-
dc.subject.keywordPlusSTIFFNESS-
dc.subject.keywordPlusNETWORKS-
dc.subject.keywordPlusMODULUS-
Appears in Collections:
KIST Article > 2019
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE