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dc.contributor.authorHong, Seong Cheol-
dc.contributor.authorMurale, Dhiraj P.-
dc.contributor.authorLee, Jun-Seok-
dc.date.accessioned2024-01-20T04:30:16Z-
dc.date.available2024-01-20T04:30:16Z-
dc.date.created2022-01-10-
dc.date.issued2016-05-
dc.identifier.issn1386-2073-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/124100-
dc.description.abstractHerein, we report the first 48-membered, dansyl-based, combinatorial fluorescent library. From the electronic and structural properties of the probes, we analyzed their optical properties and chemical yields, with an average of 49 %. The molecules were examined for their pH responses, and DS-2 and DS-45 showed blue-shifts, whereas DS-7 and DS-40 showed red-shifts in wavelength with increasing pH. Finally, cell permeability was investigated by treating SNU-2292 cells. Our results demonstrate the potential application of this library in biosensors, bio-imaging and pH indicators.-
dc.languageEnglish-
dc.publisherBENTHAM SCIENCE PUBL LTD-
dc.subjectLARGE STOKES SHIFT-
dc.subjectCHLORIDE DERIVATIZATION-
dc.subjectFLUORESCENCE PROPERTIES-
dc.subjectMASS-SPECTROMETRY-
dc.subjectACID-
dc.subjectDYES-
dc.subjectHPLC-
dc.titleCombinatorial Dansyl Library and its Applications to pH-Responsive Probes-
dc.typeArticle-
dc.identifier.doi10.2174/1386207319666160408150203-
dc.description.journalClass1-
dc.identifier.bibliographicCitationCOMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, v.19, no.5, pp.347 - 352-
dc.citation.titleCOMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING-
dc.citation.volume19-
dc.citation.number5-
dc.citation.startPage347-
dc.citation.endPage352-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000378054400002-
dc.identifier.scopusid2-s2.0-84974801163-
dc.relation.journalWebOfScienceCategoryBiochemical Research Methods-
dc.relation.journalWebOfScienceCategoryChemistry, Applied-
dc.relation.journalWebOfScienceCategoryPharmacology & Pharmacy-
dc.relation.journalResearchAreaBiochemistry & Molecular Biology-
dc.relation.journalResearchAreaChemistry-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.type.docTypeArticle-
dc.subject.keywordPlusLARGE STOKES SHIFT-
dc.subject.keywordPlusCHLORIDE DERIVATIZATION-
dc.subject.keywordPlusFLUORESCENCE PROPERTIES-
dc.subject.keywordPlusMASS-SPECTROMETRY-
dc.subject.keywordPlusACID-
dc.subject.keywordPlusDYES-
dc.subject.keywordPlusHPLC-
dc.subject.keywordAuthorCombinatorial chemistry-
dc.subject.keywordAuthordansyl chloride-
dc.subject.keywordAuthorpH sensor-
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