Fluorogenic nanoreactor assembly with boosted sensing kinetics for timely imaging of cellular hydrogen peroxide

Authors
Heo, JeongyunLim, Chang-KeunKim, YoungsunCho, Hong-JunLee, Yong-DeokMaeng, Joon-HoAhn, Dae-RoLee, SangyoupBang, JoonaPark, Soo YoungKim, Sehoon
Issue Date
2016-01
Publisher
ROYAL SOC CHEMISTRY
Citation
CHEMICAL COMMUNICATIONS, v.52, no.6, pp.1131 - 1134
Abstract
The precise detection of endogenous H2O2 has been considered to be a useful tool for understanding cell physiology. Here, we have developed a nanoreactor co-incorporated with a H2O2-responsive fluorogenicmolecule and a catalytic additive. The fast sensing kinetics allows us to visualize a subcellular response in real-time.
Keywords
FLUORESCENT-PROBES; FREE-RADICALS; HORSERADISH-PEROXIDASE; OXIDATIVE STRESS; NAD(P)H OXIDASE; BIOLOGY; FLUORESCENT-PROBES; FREE-RADICALS; HORSERADISH-PEROXIDASE; OXIDATIVE STRESS; NAD(P)H OXIDASE; BIOLOGY
ISSN
1359-7345
URI
https://pubs.kist.re.kr/handle/201004/124592
DOI
10.1039/c5cc06387f
Appears in Collections:
KIST Article > 2016
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