Electrochemical albumin sensing based on silicon nanowires modified by gold nanoparticles

Authors
Kwon, Dae HoonAn, Hyeun HwanKim, Hee-SooLee, Jong HoSuh, Sang HeeKim, Young HoYoon, Chong Seung
Issue Date
2011-03-01
Publisher
ELSEVIER
Citation
APPLIED SURFACE SCIENCE, v.257, no.10, pp.4650 - 4654
Abstract
Si nanowires (SiNWs) were modified by Au nanoparticles (AuNPs) using a self-assembled monolayer of aminopropyltriethoxysilane (APTES) and used for direct sensing of the bovine serum albumin (BSA). It was shown that repeated thermal treatment of the sensor greatly enhanced the reliability of the SiNW sensor by increasing the electrical conductivity largely from carbonization of the APTES molecules and from bringing the AuNPs in intimate contact with the SiNW surface. The AuNP-modified SiNW array sensor was able to detect 1-7 mu M of BSA. The sensor exhibited a good sensitivity over the tested concentration range and linear behavior. It is expected that the proposed label-free biosensor can be further developed to selectively detect and quantify biomolecules other than BSA. (C) 2010 Elsevier B.V. All rights reserved.
Keywords
GLUCOSE-OXIDASE; IMMOBILIZATION; FERRICYANIDE; NANOTUBES; GLUCOSE-OXIDASE; IMMOBILIZATION; FERRICYANIDE; NANOTUBES; Amperometric; Silicon nanowire; Gold nanoparticle; Albumin; APTES
ISSN
0169-4332
URI
https://pubs.kist.re.kr/handle/201004/130541
DOI
10.1016/j.apsusc.2010.12.109
Appears in Collections:
KIST Article > 2011
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