DSpace at KISTKIST Article2009

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dc.contributor.authorKim, So-Young-
dc.contributor.authorPark, Hyeong Beom-
dc.contributor.authorCho, Jung-Hyuck-
dc.contributor.authorYoo, Kyung Ho-
dc.contributor.authorOh, Chang-Hyun-
dc.date.accessioned2024-01-20T21:31:29Z-
dc.date.available2024-01-20T21:31:29Z-
dc.date.created2021-09-03-
dc.date.issued2009-05-01-
dc.identifier.issn0960-894X-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/132496-
dc.description.abstractThe synthesis of a new series of oxazolidinones having spiro[2,4]heptane moieties is described. Their in vitro antibacterial activities against both Gram-positive and Gram-negative bacteria were tested and the effect of substituents on the oxazolidinone ring was investigated. A particular compound Ih having fluoro group showed the most potent antibacterial activity. (C) 2009 Published by Elsevier Ltd.-
dc.languageEnglish-
dc.publisherPergamon Press Ltd.-
dc.subjectCONFORMATIONALLY CONSTRAINED ANALOGS-
dc.subjectIN-VITRO ACTIVITY-
dc.subjectTRICYCLIC OXAZOLIDINONES-
dc.subjectRESISTANCE-
dc.subjectQUINOLONE-
dc.subjectSAR-
dc.titleSynthesis and antibacterial activities of novel oxazolidinones having spiro[2,4]heptane moieties-
dc.typeArticle-
dc.identifier.doi10.1016/j.bmcl.2009.03.025-
dc.description.journalClass1-
dc.identifier.bibliographicCitationBioorganic & Medicinal Chemistry Letters, v.19, no.9, pp.2558 - 2561-
dc.citation.titleBioorganic & Medicinal Chemistry Letters-
dc.citation.volume19-
dc.citation.number9-
dc.citation.startPage2558-
dc.citation.endPage2561-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000265137100040-
dc.identifier.scopusid2-s2.0-64249111052-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalWebOfScienceCategoryChemistry, Organic-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.relation.journalResearchAreaChemistry-
dc.type.docTypeArticle-
dc.subject.keywordPlusCONFORMATIONALLY CONSTRAINED ANALOGS-
dc.subject.keywordPlusIN-VITRO ACTIVITY-
dc.subject.keywordPlusTRICYCLIC OXAZOLIDINONES-
dc.subject.keywordPlusRESISTANCE-
dc.subject.keywordPlusQUINOLONE-
dc.subject.keywordPlusSAR-
dc.subject.keywordAuthorOxazolidinones-
dc.subject.keywordAuthorAntibacterial activity-
dc.subject.keywordAuthorSpiro[2,4]heptane-
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