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dc.contributor.authorQuan, Wenying-
dc.contributor.authorLee, Hee Ju-
dc.contributor.authorKim, Chul Young-
dc.contributor.authorNoh, Chu Won-
dc.contributor.authorUm, Byung Hun-
dc.contributor.authorOak, Min-Ho-
dc.contributor.authorKim, Kyeong-Man-
dc.date.accessioned2024-01-21T00:00:51Z-
dc.date.available2024-01-21T00:00:51Z-
dc.date.created2021-09-03-
dc.date.issued2008-02-
dc.identifier.issn0032-0943-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/133781-
dc.description.abstractThe bioassay-guided fractionation of the MeOH extract from the root of Sophora flavescens led to the isolation of eight known prenylated flavonoids (11 -8) responsible for the in vitro anti-allergic activity. Among them, kushenol N (3), sophoraflavanone G (6), and leachianone A (7) demonstrated significant inhibition of the release of beta-hexosaminidase from cultured RBL-2H3 cells with IC50 values ranging from 15 to 30 mu M.-
dc.languageEnglish-
dc.publisherGEORG THIEME VERLAG KG-
dc.subjectANTIGEN RECEPTOR-
dc.subjectMAST-CELL-
dc.subjectFC-
dc.subjectDEGRANULATION-
dc.subjectACTIVATION-
dc.subjectKINASE-
dc.titleAnti-allergic prenylated flavonoids from the roots of Sophora flavescens-
dc.typeArticle-
dc.identifier.doi10.1055/s-2008-1034285-
dc.description.journalClass1-
dc.identifier.bibliographicCitationPLANTA MEDICA, v.74, no.2, pp.168 - 170-
dc.citation.titlePLANTA MEDICA-
dc.citation.volume74-
dc.citation.number2-
dc.citation.startPage168-
dc.citation.endPage170-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000253945800012-
dc.identifier.scopusid2-s2.0-40349091545-
dc.relation.journalWebOfScienceCategoryPlant Sciences-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalWebOfScienceCategoryIntegrative & Complementary Medicine-
dc.relation.journalWebOfScienceCategoryPharmacology & Pharmacy-
dc.relation.journalResearchAreaPlant Sciences-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.relation.journalResearchAreaIntegrative & Complementary Medicine-
dc.type.docTypeArticle-
dc.subject.keywordPlusANTIGEN RECEPTOR-
dc.subject.keywordPlusMAST-CELL-
dc.subject.keywordPlusFC-
dc.subject.keywordPlusDEGRANULATION-
dc.subject.keywordPlusACTIVATION-
dc.subject.keywordPlusKINASE-
dc.subject.keywordAuthorSophora flavescens-
dc.subject.keywordAuthorLeguminosae-
dc.subject.keywordAuthoranti-allergic activity-
dc.subject.keywordAuthorprenylated flavonoids-
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