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dc.contributor.authorSong, R-
dc.contributor.authorKim, YS-
dc.contributor.authorLee, CO-
dc.contributor.authorSohn, YS-
dc.date.accessioned2024-01-21T09:13:52Z-
dc.date.available2024-01-21T09:13:52Z-
dc.date.created2021-09-03-
dc.date.issued2003-02-17-
dc.identifier.issn0040-4039-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/138815-
dc.description.abstractA new series of DNA binding 5,10,15-tri(N-methyl-4-pyridiniumyl)porphyrin (TrisMPyP)-platinum(II) conjugates was synthesized, in which different spacer ligands were used for appropriate coordination to platinum(II) complexes. Compound 9b exhibited in vivo antitumor activity (T/C%, 294) superior to cisplatin (T/C%, 184) against the leukemia L1210 cell line. (C) 2003 Published by Elsevier Science Ltd.-
dc.languageEnglish-
dc.publisherPERGAMON-ELSEVIER SCIENCE LTD-
dc.subjectHEMATOPORPHYRIN ANALOGS-
dc.subjectPORPHYRINS-
dc.subjectDESIGN-
dc.subjectAGENTS-
dc.subjectSERIES-
dc.subjectFOLATE-
dc.titleSynthesis and antitumor activity of DNA binding cationic porphyrin-platinum(II) complexes-
dc.typeArticle-
dc.identifier.doi10.1016/S0040-4039(03)00022-4-
dc.description.journalClass1-
dc.identifier.bibliographicCitationTETRAHEDRON LETTERS, v.44, no.8, pp.1537 - 1540-
dc.citation.titleTETRAHEDRON LETTERS-
dc.citation.volume44-
dc.citation.number8-
dc.citation.startPage1537-
dc.citation.endPage1540-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000180959100002-
dc.identifier.scopusid2-s2.0-0037450508-
dc.relation.journalWebOfScienceCategoryChemistry, Organic-
dc.relation.journalResearchAreaChemistry-
dc.type.docTypeArticle-
dc.subject.keywordPlusHEMATOPORPHYRIN ANALOGS-
dc.subject.keywordPlusPORPHYRINS-
dc.subject.keywordPlusDESIGN-
dc.subject.keywordPlusAGENTS-
dc.subject.keywordPlusSERIES-
dc.subject.keywordPlusFOLATE-
dc.subject.keywordAuthorporphyrin-
dc.subject.keywordAuthorantitumor agent-
dc.subject.keywordAuthorDNA binding-
dc.subject.keywordAuthorplatinum(II)-
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