Synthesis of novel 3 '-deoxy-3 '-C-hydroxymethyl nucleosides with conformationally rigid sugar moiety as potential antiviral agents

Authors
Chun, MWKim, MJJo, UHKim, JHKim, HDJeong, LS
Issue Date
2001-03
Publisher
MARCEL DEKKER INC
Citation
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, v.20, no.4-7, pp.699 - 702
Abstract
Based on the fact that the ring expanded 3'-C-hydroxymethyl analogue of oxetanocin A exhibited potent antiviral activity, two types of conformationally rigid 3'-C-hydroxymethyl derivatives in which 2'-hydroxyl group is linked to the 4'-position or to the 6'-position were synthesized starting from 1,2;5,6-di-O-isopropylidene-D-glucose, respectively.
Keywords
OXETANOCIN; OXETANOCIN; synthesis
ISSN
1525-7770
URI
https://pubs.kist.re.kr/handle/201004/140694
DOI
10.1081/NCN-100002354
Appears in Collections:
KIST Article > 2001
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