Synthesis of novel 3 '-deoxy-3 '-C-hydroxymethyl nucleosides with conformationally rigid sugar moiety as potential antiviral agents
- Authors
- Chun, MW; Kim, MJ; Jo, UH; Kim, JH; Kim, HD; Jeong, LS
- Issue Date
- 2001-03
- Publisher
- MARCEL DEKKER INC
- Citation
- NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, v.20, no.4-7, pp.699 - 702
- Abstract
- Based on the fact that the ring expanded 3'-C-hydroxymethyl analogue of oxetanocin A exhibited potent antiviral activity, two types of conformationally rigid 3'-C-hydroxymethyl derivatives in which 2'-hydroxyl group is linked to the 4'-position or to the 6'-position were synthesized starting from 1,2;5,6-di-O-isopropylidene-D-glucose, respectively.
- Keywords
- OXETANOCIN; OXETANOCIN; synthesis
- ISSN
- 1525-7770
- URI
- https://pubs.kist.re.kr/handle/201004/140694
- DOI
- 10.1081/NCN-100002354
- Appears in Collections:
- KIST Article > 2001
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