MONITORING OF POPs FROM BIOLOGICAL FLUIDS USING HS SPME-GC/MS

Title
MONITORING OF POPs FROM BIOLOGICAL FLUIDS USING HS SPME-GC/MS
Authors
채효진김승기표희수홍종기
Issue Date
2009-06
Publisher
18th Symposium on Environmental Chemistry
Citation
, 936-937
Abstract
Rapid industrialization resulted in increasing levels of industrial by-products, including organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) in the environment and human compartments. OCPs are typical persistent organic pollutants with toxicity and bioaccumulation properties. Although the production of most OCPs has been banned for decades, they are still found in the environment due to their high persistence. The exposure of OCPs to human beings is predominantly processed through foodstuffs. PCBs make up a group of 209 individual chlorinated biphenyl rings known as congeners. The effect of exposure is liver damage, estrogenicity, thiroxine reduction. And major exposure is drinking water, food, skin contact, breathing air and bioaccumulation (mainly fat and liver). We developed analytical method for 18 OCPs and 16 PCBs determination in biological fluids, human whole blood, using headspace solid phase extraction gas chromatograph / mass spectrometer (HS SPME-GC/MS). We investigated the optimization of HS-SPME conditions, the method validation (MDL, calibration, linearity) and applied them to human blood for the monitoring of OCPs and PCBs.
URI
http://pubs.kist.re.kr/handle/201004/35469
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KIST Publication > Conference Paper
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