Measuring Stiffness of Rat Brain Cells by Atomic Force Microscope
- Measuring Stiffness of Rat Brain Cells by Atomic Force Microscope
- 이상명; 누엔티후옹; 박설경; 나경환; 김진석; 윤의성
- Stiffness; Brain Cell; AFM; Young's Modulus; Glia; Glipblastoma
- Issue Date
- Nanoscale VII
- Recently, atomic force microscopy (AFM) has become a powerful methodology for studying the biophysical properties (such as stiffness, viscoelasticity, hardness and adhesion). The unique combination of high-resolution imaging and operation in physiological environment made it useful in investigations of cell properties. A change in the physical properties, in particular cell elasticity, of tissue cells has been recognized as an indication of disease and has emerged as a marker for cellular phenotypic events associated with cell adhesion and cytoskeletal organization.
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