Synthesis and antibacterial activities of novel oxazolidinones having spiro[2,4]heptane moieties

Title
Synthesis and antibacterial activities of novel oxazolidinones having spiro[2,4]heptane moieties
Authors
김소영박형범조정혁유경호오창현
Keywords
Oxazolidinones; Antibacterial activity; Spiro[2,4]heptane
Issue Date
2009-04
Publisher
Bioorganic & medicinal chemistry letters
Citation
VOL 19, 2558-2561
Abstract
The synthesis of a new series of oxazolidinones having spiro[2,4]heptane moieties is described. Their in vitro antibacterial activities against both Gram-positive and Gram-negative bacteria were tested and the effect of substituents on the oxazolidinone ring was investigated. A particular compound Ih having fluoro group showed the most potent antibacterial activity.
URI
http://pubs.kist.re.kr/handle/201004/35779
ISSN
0960-894X
Appears in Collections:
KIST Publication > Article
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