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dc.contributor.author누럴-
dc.contributor.author남주원-
dc.contributor.author이준-
dc.contributor.author서은경-
dc.contributor.author한상범-
dc.contributor.author김동현-
dc.contributor.author진창배-
dc.contributor.author유혜현-
dc.date.accessioned2015-12-02T15:16:07Z-
dc.date.available2015-12-02T15:16:07Z-
dc.date.issued200910-
dc.identifier.citationVOL 70, NO 7/8, 1079-1085-
dc.identifier.issn0009-5893-
dc.identifier.other31295-
dc.identifier.urihttp://pubs.kist.re.kr/handle/201004/36496-
dc.description.abstractIn this study, an LC method for the simultaneous determination of six bioactive compounds from Angelica tenuissima, namely chlorogenic acid, ferulic acid, Z-ligustilide, nodakenin, decursin and decursinol angelate was developed and validated. Chromatographic analysis was carried out on a C18 column with a mobile phase consisting of 0.1% formic acid, methanol and acetonitrile at a flow rate of 0.8 mL min-1 and the effluent from the column was monitored by UV detector at 325 nm. The excellent linear behavior was observed over the investigated concentration range for reported compounds. The intra- and inter-day precision over the concentration range of compounds were lower than 1.7% (as relative standard deviation), and accuracy was between 97.2 and 106.0%. These results showed that the developed method is accurate, reproducible, and consequently applicable for the quantitation of bioactive components from the ethanolic extract of Angelica tenuissima Nakai.-
dc.publisherChromatographia-
dc.subjectColumn liquid chromatography-
dc.subjectPhenolic acids-
dc.subjectCoumarins and phthalides-
dc.subjectAngelica tenuissima-
dc.titleA Validated LC Method for Simultaneous Determination of Phenolic, Coumarin and Phthalide Compounds in the Ethanolic Extract of Angelica tenuissima-
dc.typeArticle-
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