NEW FABRICATION METHODS OF BIOACTIVE AND BIODEGRADABLE SCAFFOLDS FOR BONE TISSUE ENGINEERING

Title
NEW FABRICATION METHODS OF BIOACTIVE AND BIODEGRADABLE SCAFFOLDS FOR BONE TISSUE ENGINEERING
Authors
정영미김수희김상헌김수현
Keywords
Poly(lactide-co-glycolide); novel sintering; supercritical fluid; composite scaffold
Issue Date
2009-11
Publisher
2009 Biofoam
Abstract
Bioceramic and polymers have been used as matrices for bone tissue engineering, and successful bone regeneration depends on cellular interaction with these matrices. The aim of this study was to fabricate polymer/ceramics composites with a novel sintering method. Also, we prepared homogenous porous poly(lactide-co-glycolide (PLGA) scaffolds in the supercritical CO2. These scaffolds had homogenous porous structure and high tensile and compressive mechanical properties compared to the scaffold prepared by conventional solvent casting method. This study revealed that generating bioactive and porous polymer scaffolds with novel sintering method or supercritical fluid technique could be useful for bone tissue engineering.
URI
http://pubs.kist.re.kr/handle/201004/36598
Appears in Collections:
KIST Publication > Conference Paper
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