NEW FABRICATION METHODS OF BIOACTIVE AND BIODEGRADABLE SCAFFOLDS FOR BONE TISSUE ENGINEERING
- NEW FABRICATION METHODS OF BIOACTIVE AND BIODEGRADABLE SCAFFOLDS FOR BONE TISSUE ENGINEERING
- 정영미; 김수희; 김상헌; 김수현
- Poly(lactide-co-glycolide); novel sintering; supercritical fluid; composite scaffold
- Issue Date
- 2009 Biofoam
- Bioceramic and polymers have been used as matrices for bone tissue engineering, and successful bone regeneration depends on cellular interaction with these matrices. The aim of this study was to fabricate polymer/ceramics composites with a novel sintering method. Also, we prepared homogenous porous poly(lactide-co-glycolide (PLGA) scaffolds in the supercritical CO2. These scaffolds had homogenous porous structure and high tensile and compressive mechanical properties compared to the scaffold prepared by conventional solvent casting method. This study revealed that generating bioactive and porous polymer scaffolds with novel sintering method or supercritical fluid technique could be useful for bone tissue engineering.
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