Biodegradable PLGA Coating on Biomedical Metal Implants Using Electrospraying

Title
Biodegradable PLGA Coating on Biomedical Metal Implants Using Electrospraying
Authors
조성배박철호박귀덕정동준한동근
Keywords
전기분사; 의료용 금속 임플란트; PLGA 고분자 코팅; biomedical metal; electrospray; PLGA coating; film formation; stent
Issue Date
2009-11
Publisher
폴리머; Polymer Korea
Citation
VOL 33, NO 6, 620-624
Abstract
Biomedical metal implants have been used clinically for replacement, restoration, or improvement of injury bodies based on high mechanical properties, but it has some risks such as the inflammatory, late thrombosis, or restenosis due to the low biocompatibility and toxicity. In various techniques of surface treatment developed to preserve these drawbacks, this study examined the electrospray coating technology with biodegradable poly(lactic-co-glycoic acid) (PLGA) on metal surface. Based on fundamental examination of electrospraying and solution parameters, the surface morphology of coated film was closely related to the boiling point of solvent, in-flight distance, and droplet size. The thickness of polymer film was linearly proportional to the emerged volume. This result exhibits that the polymeric droplets were continuously deposited on the polymer film. Therefore, the electrospray coating technology might be applied into the fabrication of single/multi-layered polymer film in nano-/micro-thickness and the control of the topology for biomedical metal implants including stents.
URI
http://pubs.kist.re.kr/handle/201004/36646
ISSN
0379-153X
Appears in Collections:
KIST Publication > Article
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE