Multifunctional Nanoparticles for Molecular Imaging

Title
Multifunctional Nanoparticles for Molecular Imaging
Authors
강은아김광명권익찬
Keywords
Bioimaging; Multimodality; Nanoparticles; Activatable; Targeting; Biodistribution
Issue Date
2009-02
Publisher
대한의사협회지; Journal of the Korean Medical Association.
Citation
VOL 52, NO 2, 125-134
Abstract
Molecular imaging is a bioimaging that can detect biochemically and genetically relevant events in molecular level in cells and tissues via quantitative imaging signal. Molecular imaging provides potential advantages to examine early diagnosis of specific diseases, to screen new candidates of a drug, to monitor therapeutic effects in real time, and to communicate with both diagnosis and therapeutics. These diverse advantages of molecular imaging can be allowed by development of nanoplatform technology. The nanoplatform-based probes for molecular imaging is widely investigated to grant multimodal molecular imaging and drug delivery together with medical imagings, which includes the issues of biocompatibility, targeting moiety, proteasespecific peptide substrate, quenching/dequenching system etc. In this paper, nanoplatformbased probes are reviewed in aspects of cancer targeting for diagnosis and therapy and multimodal molecular imaging with inorganic/organic hybrid nanoparticles.
URI
http://pubs.kist.re.kr/handle/201004/37047
ISSN
0023-4028
Appears in Collections:
KIST Publication > Article
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