Intelligent Drug Delivery Systems
- Intelligent Drug Delivery Systems
- 오유경; Peter Senter; 송수창
- Issue Date
- Bioconjugate chemistry
- VOL 20, NO 10, 1813-1815
- In summary, the 2009 International Symposium on Intelligent
Drug Delivery Systems featured research in areas of great
promise for new therapeutics. In particular, new micellar,
liposomal, and hydrogel formulations allow for extended drug
release, and new applications of water-insoluble drugs that are
otherwise difficult to administer. Developments in nanotechnologies
have produced materials that release drugs in a
sequential manner or release complementary drugs under welldefined
conditions. Specific targeting has advanced significantly,
with clinically effective antibody-drug and radionuclide conjugates.
Some of the challenges that lie ahead were illustrated
by Hiroshi Kikuchi from Eisai Corporation in Japan and Kuchan
Kimm of MSD Korea, the Korean branch of Merck & Co., both
of whom discussed the difficulties in getting novel and expensive
agents like those described in the meeting approved and widely
utilized. However, as these agents progress through clinical trials
and demonstrate activity beyond what is achievable with
conventional agents, it is expected that they will comprise the
drugs of the future. The next meeting will be held in May, 2010,
at KIST in Seoul, South Korea.
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