Migration and Conformation of Single Polymer Chain in Microbends
- Migration and Conformation of Single Polymer Chain in Microbends
- 이정용; 정현욱; 현재천; 전명석
- Migration; Conformation; Single Polymer Chain; Microbend; DNA; Rheology
- Issue Date
- 5th Pacific Rim Conference on Rheology (PRCR-5)
- VOL 5
- We have investigated the migration and conformation of single DNA molecule in microchannel with 90˚ bend by applying the Brownian dynamics (BD) simulation and commercial CFD package (Flow-3D). It has been found that there is a significant displacement change of the single molecule after passing through the microbends, depending on its starting location. The DNA molecule initially positioning near the inner (or outer) wall migrates farther toward the inner (or outer) wall after the passage of bend, which is ascribed by the centripetal motion in bend regime. In addition, the relationship between the extension of single molecule and flow characteristics has been correlated by changing shear rate and channel width.
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