New terpenoid naphthoquinones from a marine actinomycete, strain CNQ-509
- New terpenoid naphthoquinones from a marine actinomycete, strain CNQ-509
- 박진수; 권학철; Paul R. Jensen; William Fenical
- Marine bacterium; actinomycete; new terpenoid naphthoquinone
- Issue Date
- Society for Industrial Microbiology 60th Annual Meeting
- As part as our continuous research on the biological and chemical diversity of marine
actinomycetes, we recognized a variety of new actinomycete taxa occur in the ocean. One of
these new marine-derived actinomycetes related to the genus Streptomyces, that is proving to
be of significant chemical interest, has been tentatively designated MAR4. The chemical
investigation of a cultured MAR4 strain, CNQ-509, that was isolated from a marine sediment
sample, led to the isolation of two new naphthoquinone derivatives (1 and 2), together with a
previously reported debromomarinone. The structures of these compounds were consisted of
two separated substructures, a naphthoquinone and a terpenoid. The analysis of spectral data
and chemical modifications provided the full structures of compounds 1 and 2.
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