Non-invasive Imaging Of Gene Silencing Efficacy of Nano-sized siRNA Delivery System In Tumor-bearing Mice

Title
Non-invasive Imaging Of Gene Silencing Efficacy of Nano-sized siRNA Delivery System In Tumor-bearing Mice
Authors
이소진이승영민솔기허명숙최귀원권익찬최용석김광명
Issue Date
2010-05
Publisher
분자영상학회
Abstract
Recent imaging techniques are very useful to diagnosis and increase therapy efficiency of diverse diseases. siRNA therapy has a hurdle for its’ clinical application due to difficulty in delivery to target site. Therefore we developed a novel nano-sized siRNA carrier system and examined the biodistribution and gene silencing of this system in vitro and in vivo, using fluorescent imaging techniques.
URI
http://pubs.kist.re.kr/handle/201004/38840
Appears in Collections:
KIST Publication > Conference Paper
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