IRINOTECAN-LOADED NANOPARTICLES BASED ON HYALURONIC ACID FOR TUMOR IMAGING AND THERAPY
- IRINOTECAN-LOADED NANOPARTICLES BASED ON HYALURONIC ACID FOR TUMOR IMAGING AND THERAPY
- 최기영; 최귀원; 정서영; 박재형; 김광명
- Issue Date
- Controlled Release Society
- Theranostic nanoparticles based on hyaluronic acid (HA-NPs) were successfully synthesized.
Biodistribution and tumor targeting characteristics of HA-NPs were evaluated with NIRF imaging techniques.
Pegylated HA nanoparticles (HA-NP-Ps) were applied to tumor imaging and therapy.
It was demonstrated that the HA-NPs could deliver anti-cancer drugs and release the drugs at disease sites, resulting in increased therapeutic efficacy and reduced side effects.
This system can be used as a platform technology to detect and treat various tumors.
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