Fabrication of a nanocoupled substrate and its effect on polymer stability for stent application
- Fabrication of a nanocoupled substrate and its effect on polymer stability for stent application
- 조성배; 이봉수; 박귀덕; 정동준; 한동근
- Fabrication; nanocoupled substrate; polymer stability
- Issue Date
- 2010년 한국생체재료학회 제18차 학술대회
- , 75-75
- Coronary artery disease (CAD) is a major health threat worldwide. Currently the most dependable therapeutic approach is to use stent, a circular mesh-type medical device with a very small diameter. In fact, the use of bare metal stent (BMS) or drug-eluting stent (DES) saves the lives of many patients after immediate stent implantation. However DES can be vulnerable to delamination of the coated polymer from the metal stent surface. This interface between polymer and metal needs to be secured. For this purpose, we introduced a nanocouling concept that utilizes graftiing method of surface-initiated ring opening polymerization (SI-ROP). It is expected that a nanocoupled layer can play a role in stabilizing the interface.
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