락타이드의 개환중합에 의해 나노커플링된 생체적합성 스테인레스스틸 표면의 접착안정성 개선
- 락타이드의 개환중합에 의해 나노커플링된 생체적합성 스테인레스스틸 표면의 접착안정성 개선
- 조성배; 이봉수; 최지연; 박귀덕; 정동준; 한동근
- 락타이드; 개환중합; 생체적합성; 나노커플링
- Issue Date
- 제42회 대한의용생체공학회 추계학술대회
- , 33-33
- Bare metal stent (BMS) is very useful in patients of coronary artery disease (CAD) but often elicits inflammation, thrombosis, and even restenosis. To prevent this problem, a drug-elubng stent (DES) has been developed and found effective in reducing restenosis. But DES on which Polymer coated is a delaminiation of the sub-micrometer scale between polymeric layer and the metal surface, after a polymeric layer was coated onto metal surface by electrospraying. This separation inhibits interfacial adhesion between them, leading to unstable state in their adhesion. We introduced a nanocoupling concept by the grafting method such as surface-initiated ring opening polymenzation (SI-ROP) L-lactide (LA) was
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