Fast identification of flanonoids in the roots of Sophora flavescens by on-flow LC-NMR

Title
Fast identification of flanonoids in the roots of Sophora flavescens by on-flow LC-NMR
Authors
김수진김상민김민철강석우엄병헌
Keywords
LC-hyphenated; on-flow LC-NMR; prenyl-flavonoid; Sophora flavescens
Issue Date
2010-12
Publisher
JOURNAL OF MEDICINAL PLANTS RESEARCH
Citation
VOL 4, NO 23, 2452-2459
Abstract
Sophora flavescens Ait (Leguminosae) is a Chinese herbal medicine. Sophorae radix, the dried roots of S. flavescens, has been used for various diseases including atherosclerosis and arrhythmias. For the direct identification of the compounds present in Sophorae radix, the hyphenated LC-NMR technique has been applied. WET solvent suppression and scout scan techniques were used to suppress solvent peaks in on-flow LC-NMR experiment. Six prenylflavonoids were identified successfully as kushenol U (1), kurarinone (2), sophoraflavanone G (3), leachianone A (4), kuraridin (5) and kushenol A (6).
URI
http://pubs.kist.re.kr/handle/201004/39212
ISSN
1996-0875
Appears in Collections:
KIST Publication > Article
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