A Three-Dimensional and Sensitive Bioassay Based on Nanostructured Quartz Combined with Viral Nanoparticles

Title
A Three-Dimensional and Sensitive Bioassay Based on Nanostructured Quartz Combined with Viral Nanoparticles
Authors
이종환김정숙박진승이원배이경은한성식이규백이지원
Issue Date
2010-06
Publisher
Advanced functional materials
Citation
VOL 20, NO 12, 2004-2009
Abstract
An effective mask-free method for fabricating high-aspect-ratio pillarlike nanostructures over a large area of a quartz surface via a simple O2 and CF4 two-step reactive ion etching (RIE) procedure is developed. The nanostructured quartz surfaces are successfully combined with the engineered viral particles derived from hepatitis B virus capsid, yielding a novel 3D assay system with attomolar sensitivity, which has great potential for use in sensitive and early detection of various disease markers.
URI
http://pubs.kist.re.kr/handle/201004/39271
ISSN
1616-301X
Appears in Collections:
KIST Publication > Article
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