Isolation of mutants in Clostridium tyrobutyricum for improved tolerance to lignin

Title
Isolation of mutants in Clostridium tyrobutyricum for improved tolerance to lignin
Authors
이경민김기연민경선조민호한성옥엄영순상병인
Keywords
C. tyrobutyricum; Gamma-ray irradiation; lignin
Issue Date
2011-04
Publisher
한국생물공학회
Abstract
Recently, biomass is regarded as one of the important resources because that can be converted to biofuels which is the most interested issue in the field of biotechnology. Many biochemical processes have adapted saccharificated land plants and microorganisms such as Clostridium tyrobutyricum to produce biofuels. In the process, most of the microorganism convert the lignocellulose hydrolysate to bioenergy (butyric acid) under strict anaerobic condition. The land plants contains about 26% lignin (phenolics) in general. However, lignin (phenolics) often inhibits the cell growth and consequently the productivity in the process. In this study, we isolated mutated Clostridium tyrobutyricum that have tolerance to lignin by gamma-ray irradiation. These mutants exhibited the remarkably improved cell growth and the production of butyric acid to the level of the control.
URI
http://pubs.kist.re.kr/handle/201004/39736
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KIST Publication > Conference Paper
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