Gombapyrones E and F, New α-Pyrone Polyenes Produced by Streptomyces sp. KMC-002

Title
Gombapyrones E and F, New α-Pyrone Polyenes Produced by Streptomyces sp. KMC-002
Authors
박현봉양현옥이강노권학철
Keywords
New compound; Gombapyrone; Streptomyces; Microorganism; Bacterial metabolites; α-Pyrone; Polyene
Issue Date
2011-04
Publisher
Molecules
Citation
VOL 16, NO 5, 3519-3529
Abstract
Microorganism-derived polyene polyketides have been shown to display a variety of biological activities and have attracted great interest due to their structurally intriguing chemical diversity. Two new polyenes were isolated from a culture broth of Streptomyces sp. KMC-002 obtained from a soil sample in an abandoned mine. The structures of these compounds were determined to be α-pyrone-containing polyene analogues through analyses of HRFABMS, UV and NMR data, and were named Gombapyrones E (1) and F (2). Gombapyrone E (1) showed antibacterial activity against Micrococcus luteus, Enterococcus hirae, Staphylococcus aureus and MRSA.
URI
http://pubs.kist.re.kr/handle/201004/39742
ISSN
1420-3049
Appears in Collections:
KIST Publication > Article
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE