Multifunctional Chitosan Nanoparticles for Tumor Imaging and Therapy

Title
Multifunctional Chitosan Nanoparticles for Tumor Imaging and Therapy
Authors
이지영구희범이동은최귀원권익찬김광명
Keywords
Chitosan; Molecular imaging; Nanoparticle; Tumor
Issue Date
2011-09
Publisher
Advances in polymer science; Fortschritte der Hochpolymeren-Forschung
Citation
VOL 243, 139-162
Abstract
Chitosan and its derivatives have been widely used for various biomedical applications because of their unique chemical and biological characters. The amine groups in the backbone of chitosan allow chemical modification to change the physical properties of chitosan. Based on hydrophobic or charge interactions with this chitosan polymer backbone, stable self-assembled nanoparticles can be fabricated in aqueous condition. These nanosized structures enable intravenous injection and show large accumulation in tumor tissue, indicating great potential in imaging and drug delivery. The main objective of this review is to introduce various chitosan nanoparticles and their recent applications for tumor diagnosis and therapy.
URI
http://pubs.kist.re.kr/handle/201004/40290
ISSN
0065-3195
Appears in Collections:
KIST Publication > Article
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