Oploxynes A and B, Polyacetylenes from the stems of Oplopanax elatus

Title
Oploxynes A and B, Polyacetylenes from the stems of Oplopanax elatus
Authors
양민철권학철김영주이강노양현옥
Issue Date
2010-05
Publisher
Journal of natural products
Citation
VOL 73, NO 5, 801-805
Abstract
Two new polyacetylenes, oploxynes A (1) and B (2), and the known oplopandiol (3) and falcarindiol (4) were isolated from the stem of Oplopanax elatus. The structures of compounds 1 and 2 were determined to be 9,10-epoxyheptadeca- 4,6-diyne-3,8-diol and 10-methoxyheptadeca-4,6-diyne-3,8,9-triol, respectively, on the basis of their UV, MS, and NMR data. The absolute configurations of these compounds were determined using the modified Mosher’s method and acetonide formation. Oploxyne A (1), oplopandiol (3), and falcarindiol (4) inhibited the formation of nitric oxide (NO) and prostaglandin E2 (PGE2) in lipopolysaccharide (LPS)-induced murine macrophage RAW 267.7 cells.
URI
http://pubs.kist.re.kr/handle/201004/40623
ISSN
0163-3864
Appears in Collections:
KIST Publication > Article
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE