Plastoquinones from Sargassum yezoense
- Plastoquinones from Sargassum yezoense; Chemical Structures and Effects on the Activation of Peroxisome Proliferator-Activated Receptor Gamma
- Chemical Structures and Effects on the Activation of Peroxisome Proliferator-Activated Receptor Gamma
- 김민철; 권학철; 김수남; 김형섭; 엄병헌
- Brown algae; PPAR gamma agonist; sargassacea; plastoquinones; Sargassum yezoense; plastozuinone
- Issue Date
- Chemical & pharmaceutical bulletin
- VOL 59, NO 7, 834-838
- Four new plastoquinones, together with two known compounds, sargahydroquinoic acid and sargaquinoic
acid, were isolated from the brown alga, Sargassum yezoense collected from the eastern coast of Korea. The
structures of these compounds were elucidated based on spectroscopic analyses including NMR and MS. Their
structures designated as meroterphenol A (1), B (2), C (3) and D (4) were characterized by a 6-methyl-1,4-benzohydroquinone
moiety with an oxygenated diterpenoic acid chain. Meroterphenols A—D showed potent activation
effects on peroxisome proliferator-activated receptor gamma (PPARγ ).
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