PREPARATION OF LACTIDE-GRAFTED MAGNESIUM OXIDE NANOPARTICLES AND THEIR EFFECT ON pH NEUTRALIZATION
- PREPARATION OF LACTIDE-GRAFTED MAGNESIUM OXIDE NANOPARTICLES AND THEIR EFFECT ON pH NEUTRALIZATION
- 금창헌; 최지연; 김준태; 박귀덕; 안동준; 한동근
- Issue Date
- The 12th Pacific Polymer Conference
- Biodegradable polymers such as poly(L-lactide) (PLLA) and poly(lactide-co-glycolide) (PLGA) have been attracted in various biomedical applications. However, degradation of polyester can decrease the mechanical properties and increase the acidity of the environment which can induce inflammation. In order to neutralize the acidic environment caused during polymer degradation, L-lactide (LA) was grafted on the surface of MgO nanoparticles via surface-initiated ring-opening polymerization. The PLLA-grafted MgO nanoparticles were characterized by FTIR, SEM, pH meter, and TGA. Surface-modified MgO nanoparticles showed pH neutralization effect and increased the pH with the MgO concentration. The surface-modified MgO nanoparticles-reinforced PLLA composites were also fabricated and their modulus increased significantly compared to those of the control PLLA. MgO nanoparticles-reinforced PLLA composites demonstrated great potential as biodegradable and biocompatible stents or implants which can avoid inflammation.
- Appears in Collections:
- KIST Publication > Conference Paper
- Files in This Item:
There are no files associated with this item.
- RIS (EndNote)
- XLS (Excel)
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.