Electrochemical albumin sensing based on silicon nanowires modified by gold nanoparticles
- Electrochemical albumin sensing based on silicon nanowires modified by gold nanoparticles
- 권대훈; 안현환; 김희수; 이종호; 서상희; 김영호; 윤종승
- Amperometric; Silicon nanowir; Gold nanoparticle; Albumin; APTES
- Issue Date
- Applied surface science
- VOL 257, NO 10, 4650-4654
- Si nanowires (SiNWs) were modified by Au nanoparticles (AuNPs) using a self-assembled monolayer of
aminopropyltriethoxysilane (APTES) and used for direct sensing of the bovine serum albumin (BSA). Itwas
shown that repeated thermal treatment of the sensor greatly enhanced the reliability of the SiNW sensor
by increasing the electrical conductivity largely from carbonization of the APTES molecules and from
bringing the AuNPs in intimate contact with the SiNW surface. The AuNP-modified SiNW array sensor
was able to detect 1–7 M of BSA. The sensor exhibited a good sensitivity over the tested concentration
range and linear behavior. It is expected that the proposed label-free biosensor can be further developed
to selectively detect and quantify biomolecules other than BSA.
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