Electrochemical albumin sensing based on silicon nanowires modified by gold nanoparticles

Title
Electrochemical albumin sensing based on silicon nanowires modified by gold nanoparticles
Authors
권대훈안현환김희수이종호서상희김영호윤종승
Keywords
Amperometric; Silicon nanowir; Gold nanoparticle; Albumin; APTES
Issue Date
2011-03
Publisher
Applied surface science
Citation
VOL 257, NO 10, 4650-4654
Abstract
Si nanowires (SiNWs) were modified by Au nanoparticles (AuNPs) using a self-assembled monolayer of aminopropyltriethoxysilane (APTES) and used for direct sensing of the bovine serum albumin (BSA). Itwas shown that repeated thermal treatment of the sensor greatly enhanced the reliability of the SiNW sensor by increasing the electrical conductivity largely from carbonization of the APTES molecules and from bringing the AuNPs in intimate contact with the SiNW surface. The AuNP-modified SiNW array sensor was able to detect 1–7 M of BSA. The sensor exhibited a good sensitivity over the tested concentration range and linear behavior. It is expected that the proposed label-free biosensor can be further developed to selectively detect and quantify biomolecules other than BSA.
URI
http://pubs.kist.re.kr/handle/201004/41989
ISSN
0169-4332
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KIST Publication > Article
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