Identification of Cancer cell-line origins using fluorescence image-based phenomic screening

Title
Identification of Cancer cell-line origins using fluorescence image-based phenomic screening
Authors
이준석김윤경김한조SIti HajarYee Ling Tan강남영Shin Hui Ng윤창노장영태
Keywords
fluorescence probe; image-based analysis; phenomic screening
Issue Date
2012-02
Publisher
PLoS ONE
Citation
VOL 7, NO 2, e32096-1-e32096-8
Abstract
Universal phenotyping techniques that can discriminate among various states of biological systems have great potential. We applied 557 fluorescent library compounds to NCI’s 60 human cancer cell-lines (NCI-60) to generate a systematic fluorescence phenotypic profiling data. By the kinetic fluorescence intensity analysis, we successfully discriminated the organ origin of all the 60 cell-lines.
URI
http://pubs.kist.re.kr/handle/201004/42086
ISSN
19326203
Appears in Collections:
KIST Publication > Article
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