Optimization of hexanoic acid production from sucrose as a sole carbon source by Megasphaera sp.
- Optimization of hexanoic acid production from sucrose as a sole carbon source by Megasphaera sp.
- 최기은; 전병승; 오민규; 상병인; 엄영순
- Issue Date
- 2011 추계화학공학회
- Hexanoic acid, a six-carbon straight-chain fatty acid, can be produced from sustainable bio-resources and it is a potentially useful industrial chemical and bio-fuel precursor. In this study, hexanoic acid production from sucrose was investigated with Megasphaera sp. Megasphaera sp. is a strictly anaerobic bacterium normally found in the rumen of sheep and cattle which is capable of making hexanoic acid as a major end-product from complex medium (mPYS medium) with sucrose 20 g/L and 3 g/L sodium acetate. To investigate the effect of pH of the medium on hexanoic acid production, cultivation at the initial pH values of 5, 5.5, 6, 6.5, 7, 7.5, and 8 were performed. Hexanoic acid production was the maximum at the initial pH of 5.5 at 37 ℃. Moreover, acetate, butyrate and yeast extract were respectively added to the medium for increasing the hexanoic acid production. Further study is required to investigate the optimal fermentation conditions for hexanoic acid production using an efficient statistical experimental design and analysis.
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