Development of aptamer sensor by using total internal reflection ellipsometry
- Development of aptamer sensor by using total internal reflection ellipsometry
- 정용우; 이석; 우덕하; 김재헌
- aptamer; ellipsometry
- Issue Date
- 제19회 광전자 및 광통신 학술회의 논문
- , 290-291
- Aptamer is an oligonucleotide having high affinity and selectivity for various target compounds. In this work, we studied interactions between thrombin-binding aptamer (TBA) and thrombin by using total internal reflection ellipsometry (TIRE). TIRE system could sensitively detect responses between TBA and thrombin, and monitor these interactions in real time. As a result, we expect that TIRE sensor system could be effectively used as the optical sensor in usual bio-molecule interactions.
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