Self-Deprotonation and Colorization of 1,3-Bis(dicyanomethylidene)indan in Polar Media: A Facile Route to a Minimal Polymethine Dye for NIR Fluorescence Imaging

Title
Self-Deprotonation and Colorization of 1,3-Bis(dicyanomethylidene)indan in Polar Media: A Facile Route to a Minimal Polymethine Dye for NIR Fluorescence Imaging
Authors
허정윤임창근황동렬신지영정서영박수영권익찬김세훈
Keywords
fluorescence; fluorescent probes; imaging agents; nearinfrared spectroscopy; polymethines
Issue Date
2012-07
Publisher
Chemistry : a European journal
Citation
VOL 18, NO 28, 8699-8704
Abstract
Colorless 1,3-bis(dicyanomethylidene)indan is an organic acid (pKa≈3.0) that turns blue in polar media owing to self-deprotonation. Moreover, its colored conjugate base shows potential as a minimal anionic polymethine dye for probing biomolecules in cells and in vivo through noncovalent complexation and near-infrared fluorescence signaling.
URI
http://pubs.kist.re.kr/handle/201004/43037
ISSN
09476539
Appears in Collections:
KIST Publication > Article
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