Isolation of Prenylated Isoflavonoids from Cudrania tricuspidata Fruits that Inhibit A2E Photooxidation

Title
Isolation of Prenylated Isoflavonoids from Cudrania tricuspidata Fruits that Inhibit A2E Photooxidation
Authors
메즈박이희주전제승정동화김철영
Keywords
Cudrania tricuspidata; prenylated isoflavonoids; online HPLC-ABTS+ system; A2E photooxidation; 6,8-diprenylorobol; pomiferin
Issue Date
2011-09
Publisher
Natural Product Sciences
Citation
VOL 17, NO 3, 206-211
Abstract
High-performance liquid chromatography coupled to an online ABTS+-based assay (online HPLCABTS +) system was used to determine the principal antioxidants in Cudrania tricuspidata fruits. Six prenylated isoflavonoids (1 - 6) were isolated from C. tricuspidata fruits according to the online HPLC-ABTS+ system. The structures of isolated compounds, alpiniumisoflavone (1), 6,8-diprenylorobol (2), 6,8-diprenylgenistein (3), pomiferin (4), 4'-methylalpiniumisoflavone (5), and osajin (6) were identified by their retention time, UV spectra, ESI-MS, and NMR data. Among these compounds, 6,8-diprenylorobol (2) and pomiferin (4) reduced A2E photooxidation in a dose dependent manner.
URI
http://pubs.kist.re.kr/handle/201004/43283
ISSN
12263907
Appears in Collections:
KIST Publication > Article
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