Multifunctional nanoparticles for multimodal imaging and theragnosis
- Multifunctional nanoparticles for multimodal imaging and theragnosis
- 이동은; Heebeom Koo; 선인철; 류주희; 김광명; 권익찬
- Drug Delivery Systems; Diagnostic Imaging; Nanomedicine
- Issue Date
- Chemical society reviews
- VOL 41, NO 7, 2656-2672
- Nanomedicine is the biomedical application of nanoscale materials for diagnosis and therapy of disease.
Recent advances in nanotechnology and biotechnology have contributed to the development of
multifunctional nanoparticles as representative nanomedicine. They were initially developed to enable the
target-specific delivery of imaging or therapeutic agents for biomedical applications. Due to their unique
features including multifunctionality, large surface area, structural diversity, and long circulation time in
blood compared to small molecules, nanoparticles have emerged as attractive preferences for optimized
therapy through personalized medicine. Multimodal imaging and theragnosis are the cutting-edge
technologies where the advantages of nanoparticles are maximized. Because each imaging modality has
its pros and cons, the integration of several imaging agents with different properties into multifunctional
nanoparticles allows precise and fast diagnosis of disease through synergetic multimodal imaging.
Moreover, nanoparticles are not only used for molecular imaging but also applied to deliver therapeutic
agents to the disease site in order to accomplish the simultaneous imaging and therapy called
theragnosis. This tutorial review will highlight the recent advances in the development of multifunctional
nanoparticles and their biomedical applications to multimodal imaging and theragnosis as nanomedicine.
- Appears in Collections:
- KIST Publication > Article
- Files in This Item:
There are no files associated with this item.
- RIS (EndNote)
- XLS (Excel)
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.